Results 151 to 160 of about 141,828 (307)

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

open access: yesPediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang   +4 more
wiley   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang   +6 more
wiley   +1 more source

Effect of a Defective Clamp Loader Complex of DNA Polymerase III on Growth and SOS Response in Pseudomonas aeruginosa. [PDF]

open access: yesMicroorganisms, 2022
Spinnato MC   +7 more
europepmc   +1 more source

Revealing the Effects of Circular Economy, Eco‐Innovation and Industry 4.0 on Sustainability Performance and Competitive Advantage in Manufacturing Companies

open access: yesSustainable Development, EarlyView.
ABSTRACT Successful implementation of the circular economy (CE) is expected to lead companies to improve their sustainability performance and achieve competitive advantages to support the transition to a more desirable economic system. However, the body of knowledge and evidence of impacts shows fragmented and, in some cases, contradictory results ...
Rafael Mora‐Contreras   +1 more
wiley   +1 more source

Lipid Microparticle‐Based Phantoms Modeling Hepatic Steatosis for the Validation of Quantitative Imaging Techniques

open access: yesSmall Methods, EarlyView.
This paper presents a novel method for creating ultrasound phantoms that accurately replicate fat vesicle sizes encountered in Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD). This approach can improve the understanding of liver fat measurement by creating ultrasound phantoms that link different quantitative imaging techniques to ...
Connor Endsley   +11 more
wiley   +1 more source

Targeting evolution of antibiotic resistance by SOS response inhibition. [PDF]

open access: yesComput Struct Biotechnol J, 2021
Yakimov A, Bakhlanova I, Baitin D.
europepmc   +1 more source

Development of Scalable Impedance Data Collection System for Li‐Ion Batteries and State Estimation Using Neural Networks

open access: yesIEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
In recent years, the importance of accurate state estimation techniques for lithium‐ion batteries (LIBs) has been increasing. An approach that combines electrochemical impedance spectroscopy (EIS) with machine learning is highlighted as a promising method for high‐precision state estimation.
Motoya Furugori, Noboru Katayama
wiley   +1 more source

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