Results 141 to 150 of about 30,449 (250)

Accelerating Mission Engineering: Evidence of a Stratified Landscape and a Path Toward Unified Practice

Systems Engineering, EarlyView.
ABSTRACT Mission Engineering is maturing as a Systems Engineering discipline, yet adoption of its common frameworks remains stratified. This study examines whether selective adoption is observable across ME scholarship and develops a framework to address identified barriers.
James Moreland, Nathaniel Ambler, Casey LaMar, Maegen Nix, Craig Sawyer   +4 more
wiley   +1 more source

Synergistic Quinolone Sensitization by Targeting the recA SOS Response Gene and Oxidative Stress. [PDF]

Antimicrob Agents Chemother, 2021
Diaz-Diaz S, Recacha E, Machuca J, García-Duque A, Docobo-Pérez F, Blázquez J, Pascual A, Rodríguez-Martínez JM.   +7 more
europepmc   +1 more source

What Is the Return on Investment of Digital Engineering for Complex Systems Development Schedules? Findings From a Mixed‐Methods Case Study on the Post‐Production Design Change Processes of Navy Assets

Systems Engineering, EarlyView.
ABSTRACT Complex engineered systems routinely face schedule and cost overruns, along with poor post‐deployment performance. Both INCOSE and the U.S. Department of Defense (DoD) have championed Digital Engineering (DE) as a potential remedy, yet most of DE's purported benefits remain anecdotal, and its return on investment (ROI) remains poorly ...
Jannatul Shefa, Taylan G. Topcu
wiley   +1 more source

Phage provoke growth delays and SOS response induction despite CRISPR-Cas protection. [PDF]

Philos Trans R Soc Lond B Biol Sci
Pons BJ, Łapińska U, Lopes-Domingues I, Chisnall MAW, Westra ER, Pagliara S, van Houte S.   +6 more
europepmc   +1 more source

Moxifloxacin Activates the SOS Response in Mycobacterium tuberculosis in a Dose- and Time-Dependent Manner. [PDF]

Microorganisms, 2021
Iacobino A, Piccaro G, Pardini M, Fattorini L, Giannoni F.   +4 more
europepmc   +1 more source

Photocatalytic and Biotechnological Strategies for Remediation of Persistent Organic Pollutants: Mechanisms, Toxicity, and Antimicrobial Perspectives

Environmental Toxicology, EarlyView.
ABSTRACT Persistent organic pollutants (POPs) pose significant ecological and human health risks due to their persistence, bioaccumulation, toxicity, and global distribution. Conventional remediation methods are often inadequate for achieving complete mineralization, demonstrating the need for advanced and substantial approaches.
Viola O. Okechukwu, Patrick B. Njobeh, Jonathan O. Okonkwo   +2 more
wiley   +1 more source

Response to Protocol Review Scenario: Not so fast [PDF]

Lab Animal, 2014
Patricia A, Preisig, Kelly A, Fusco
openaire   +2 more sources

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

The SOS response-associated peptidase (SRAP) domain of YedK catalyzes ring opening of abasic sites and reversal of its DNA-protein cross-link. [PDF]

J Biol Chem, 2022
Paulin KA, Cortez D, Eichman BF.
europepmc   +1 more source

Fluoroquinolone-specific resistance trajectories in E. coli and their dependence on the SOS-response. [PDF]

BMC Microbiol
Teichmann L, Luitwieler S, Bengtsson-Palme J, Ter Kuile B.   +3 more
europepmc   +1 more source