The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Snapshots of Pseudomonas aeruginosa SOS response reveal structural requisites for LexA autoproteolysis. [PDF]
Vascon F +11 more
europepmc +1 more source
ABSTRACT Aims To evaluate whether information about patients' poor sense of security in hypothetical vignette scenarios increases nurses' projected intent to report safety events. Design Quantitative, cross‐sectional factorial survey vignette experiment administered online.
Patricia S. Groves +3 more
wiley +1 more source
Rapid detection of genotoxicity employing an engineered high-sensitivity and tight SOS-response biosensor in <i>Escherichia coli</i> MG1655. [PDF]
Yuan X, Hao W, Zhang C, Ji Y, Wang Y.
europepmc +1 more source
The Epistemic Harms of Botched Apologies for Past Wrongs
ABSTRACT Apologies often create expectations of meaningful change and repair. Yet when institutions or states deliver apologies for past wrongs that lack substantive reparative action, they risk deepening, rather than redressing, the harms they acknowledge.
Abraham Tobi
wiley +1 more source
Tree growth response and adaptation to climate change and climate extremes: From canopy to stem
This review synthesizes the responses and adaptations of tree growth, including canopy phenology, intra‐annual wood formation dynamics, and annual stem growth, to climate change and climate extremes. It highlights key knowledge gaps for future research to support sustainable forest management and enhance forest carbon storage under ongoing climate ...
Feiyu Yang +8 more
wiley +1 more source
The SOS Response Activation and the Risk of Antibiotic Resistance Enhancement in Proteus spp. Strains Exposed to Subinhibitory Concentrations of Ciprofloxacin. [PDF]
Zabłotni A, Schmidt M, Siwińska M.
europepmc +1 more source
In Response to “Why Burnout Is So Hard to Fix” [PDF]
openaire +2 more sources
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad +8 more
wiley +1 more source
Phagosomal granulocytic ROS in septic patients induce the bacterial SOS response. [PDF]
Chollet S +9 more
europepmc +1 more source

