Results 91 to 100 of about 17,122,186 (353)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Global and Local Persistence of Influenza A(H5N1) Virus

open access: yesEmerging Infectious Diseases, 2014
An understanding of the global migration dynamics of highly pathogenic avian influenza A(H5N1) virus is helpful for surveillance and disease prevention.
Xianbin Li   +9 more
doaj   +1 more source

The GEO600 squeezed light source

open access: yes, 2010
The next upgrade of the GEO600 gravitational wave detector is scheduled for 2010 and will, in particular, involve the implementation of squeezed light.
Alexander Khalaidovski   +14 more
core   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Quantum technology: single-photon source [PDF]

open access: yes, 2017
This report is a synthesis of my master thesis internship at the National Institute of Informatics (NII) in Tokyo, Japan, that lasted during the summer of year 2012.
Camus, Vincent
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Consider the Source: The Value of Source Code to Digital Preservation Strategies [PDF]

open access: yes, 2013
One of the major challenges in the digital preservation field is the difficulty of ensuring long-term access to digital objects, especially in cases when the software that was used to create an object is no longer current.
Castagné, Michel
core   +1 more source

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