Results 151 to 160 of about 16,051,352 (293)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Source Control in <i>Pseudomonas aeruginosa</i> Bloodstream Infections: An Overlooked Pillar in Reducing 30-Day All-Cause Mortality. [PDF]

Open Forum Infect Dis
Vena A, Bavastro M, Muccio M, Schenone M, Corcione S, Pascale R, Giacobbe DR, Mornese Pinna S, Pari B, Giovannenze F, Geremia N, Mikulska M, Taddei E, Sangiorgi F, Bavaro DF, Scaglione V, Sisto S, Taramasso L, Vassia V, Bartoletti M, De Rosa FG, Giannella M, Viale P, Bassetti M, SITA GIOVANI (Young Investigators Group of the Società Italiana Terapia Antinfettiva, SITA GIOVANI (Young Investigators Group of the Società Italiana Terapia Antinfettiva .   +25 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Surgical source control in a patient with septic shock due to severe emphysematous pyelonephritis. [PDF]

Trauma Surg Acute Care Open, 2023
Kono K, Nagao T, Kanda T, Tomonaga A, Ito K.   +4 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Right Knee Ureaplasma Septic Arthritis in an Immunocompromised Host, Requiring Right Hip Disarticulation for Definitive Source Control. [PDF]

J Orthop Case Rep
Yang C, Najim Y, Suraya ZA.
europepmc   +1 more source

Efficiency of Nonpoint Source Pollution Instruments with Externality Among Polluters:An Experimental Study. [PDF]

In nonpoint source pollution problems, the regulator does not observe each polluter’s individual emission, which prevents him from using the conventional policy instruments. Therefore new instruments have been designed to regulate this type of pollution.
Marc Willinger, Anastasios Xepapadeas, François Cochard   +2 more
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Design Rainfall Change of Rainwater Source Control Facility to Meet Future Scenarios in Beijing. [PDF]

Int J Environ Res Public Health, 2023
Wang X, Zhao Z, Zhang Z, Ren M, Sagris T.   +4 more
europepmc   +1 more source

Mosquito Control Commission, operating manual

, 1935
This item is the operating manual of the Mosquito Control Commission for the State of Delaware. Its creation in August of 1935 is attributed to Pleasant McCarty.
Mosquito Control Commission
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