Results 171 to 180 of about 4,195,304 (299)

Genetic fecal source identification in urban streams impacted by municipal separate storm sewer system discharges. [PDF]

PLoS One, 2023
Diedrich A, Sivaganesan M, Willis JR, Sharifi A, Shanks OC.   +4 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Heavy Metals in River Sediments: Contamination, Toxicity, and Source Identification-A Case Study from Poland. [PDF]

Int J Environ Res Public Health, 2022
Sojka M, Jaskuła J.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Ecological Risk Assessment and Source Identification of Potential Toxic Elements in Farmland Soil of Nanyang Basin, China. [PDF]

Toxics
He W, Fei X, Guo H, Zhang G, Li M, Jiang Y.   +5 more
europepmc   +1 more source

Source Identification and Genome-Wide Association Analysis of Crown Rot Resistance in Wheat. [PDF]

Plants (Basel), 2022
Pu L, Goher F, Zeng M, Wu D, Zeng Q, Han D, Li C.   +6 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Chemical characterization and source identification of PM_2.5 in the Huaxi urban area of Guiyang. [PDF]

Sci Rep
Li Y, Wang X, Xu P, Gui J, Guo X, Yan G, Fei X, Yang A.   +7 more
europepmc   +1 more source

Size-segregated source identification of water-soluble and water-insoluble metals and trace elements of coarse and fine PM in central Los Angeles. [PDF]

Atmos Environ (1994), 2023
Mahdi Badami M, Tohidi R, Jalali Farahani V, Sioutas C.   +3 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source