Results 131 to 140 of about 10,524,393 (255)
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Experimenting with Small Open-Source Models for Practical Use
This lightning talk explores whether small, open-source language models can be used on less powerful servers for practical, real-world applications. The talk will share preliminary findings and discuss future directions, including exploring additional ...
Jiang, Lingling
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Title from guide. Title on publisher's web site: Gay rights movement. Series 9. Gay and lesbian community, support, and spirit: Selected newspapers and periodicals from the Gay, Lesbian Bisexual and Transgender Historical Society.
Primary Source Microfilm
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This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Source de Teplitz (Bahème) la meilleure des eaux de tables.
SOURCE DE TEPLITZ (BAHÈME) LA MEILLEURE DES EAUX DE TABLES. Source de Teplitz (Bahème) la meilleure des eaux de tables. ( -
Source de Teplitz
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Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Cornell High Energy Synchrotron Source (CHESS)
Cornell High Energy Synchrotron Source (CHESS) "is a high-intensity high-energy X-ray source" for research in many scientific fields including materials science, physics, and chemistry.
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High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Geochemical character and material source of sediments in the eastern Philippine Sea
Based upon analyses of grain-size, rare earth element (REE) compositions, elemental occurrence phases of REE, and U-series isotopic dating, the sediment characteristics and material sources of the study area were examined for the recently formed deep-sea
Li AnChun +3 more
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