Results 111 to 120 of about 5,011,192 (299)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Stabilization of Electrical Parameters of Machine-Converter Voltage Source

open access: yesEAI Endorsed Transactions on Energy Web, 2018
The paper is devoted to development of Machine-Converter Source (MCS), which forms the output voltage waveform of electric generator as sum of EMFs with near frequencies.
Yu. N. Dementyev   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Relations between source parameters for large Persian earthquakes

open access: yesAnnals of Geophysics, 2015
Empirical relationships for magnitude scales and fault parameters were produced using 436 Iranian intraplate earthquakes of recently regional databases since the continental events represent a large portion of total seismicity of Iran.
Majid Nemati, Mohammad Tatar
doaj   +1 more source

Introduction to seismic sources and source paramet

open access: yes, 1999
Additional keywords: geological fault, fractal geologic systems, rupture kinematics and dynamics, induzierte seismische Ereignisse, Herdparameter, makroseismische Intensitaet, Magnitude, seismische Energie, seismisches Herdspektrum, seismisches Moment, Groesse des Herdgebietes, Herdflaechenloesungen, geologische Verwerfungen, fraktale geologische ...
Bormann, P., Grosser, H.
openaire   +2 more sources

Update of ILC Positron Source Parameters

open access: yes, 2016
POSIPOL 2016 Workshop, Orsay, France, 14 Sep 2016 - 16 Sep 2016 ; (2016).
Ushakov, Andriy, Riemann, Sabine
openaire   +2 more sources

Simplified method for measuring the impedance of RF power sources - A concept [PDF]

open access: yes, 1970
Bolometer detector and bridge circuit measure the RF power. A varied bridge reference resistor achieves maximum power transfer allowing the output impedance of the RF source to be determined from the known circuit ...
Oakley, E. C.
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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