Results 41 to 50 of about 1,513,929 (268)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Seismological aspects of the Cairo earthquake, 12th October 1992

open access: yesAnnals of Geophysics, 2000
On 12 October 1992 a significant earthquake (MB = 5.8) occurred southwest of Cairo in the vicinity of the Dahshour region. For the mainshock, an average moment release M 0 = 9.70E17 n-m; a fault length = 13.8 km; an average displacement = 0.22 m; a ...
E. M. Ibrahim   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Quick output parameters related to the 23 January 2024 MS7.1 Wushi earthquake in the Aksu region of Xinjiang

open access: yes地震科学进展
On January 23,2024 at 02:09 (Beijing time), the MS7.1 earthquake occurred in Wushi county, Aksu Prefecture, Xinjiang. The Institute of Geophysics, China Earthquake Administration initiated a rapid response after the earthquake, organized researchers in ...
Zhe Zhang   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Modelling eruptive source parameters in distributed volcanic fields

open access: yesVolcanica, 2021
Vent opening hazard models are routinely used as inputs for assessing distal volcanic hazards (lava flows, tephra fallout) in distributed volcanic fields.
Elisabeth Gallant   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Determination of focal mechanism solutions of the earthquakes with M≥4.0 occurred in the mainland of China during July to December 2024

open access: yes地震科学进展
In this paper,the regional full waveform inversion using the broadband waveforms recorded by China Seismic Network were conducted, and the focal mechanism solutions of the 38 earthquakes with M≥4.0 occurred in the mainland of China during July to ...
Shanshan Liang   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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