Results 51 to 60 of about 1,513,929 (268)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Universal compression of Gaussian sources with unknown parameters

open access: yesCoRR, 2014
For a collection of distributions over a countable support set, the worst case universal compression formulation by Shtarkov attempts to assign a universal distribution over the support set. The formulation aims to ensure that the universal distribution does not underestimate the probability of any element in the support set relative to distributions ...
Alon Orlitsky, Narayana P. Santhanam
openaire   +2 more sources

A widely felt Tremor (ML 3.5) of 12 April 2020 in and around NCT Delhi in the backdrop of prevailing COVID-19 pandemic lockdown: analysis and observations

open access: yesGeomatics, Natural Hazards & Risk, 2020
An earthquake of small magnitude (ML3.5) occurred on 12 April 2020 near the east district boundary of NCT, Delhi with maximum PGA for the event observed to be 14.13 gals. A few smaller aftershocks also occurred in the area.
Ajeet P. Pandey   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Characteristic Analysis of the MS6.0 Ma'erkang Earthquake Sequence on Jun. 10, 2022

open access: yesJournal of Risk Analysis and Crisis Response (JRACR)
On June 10, 2022, the MS6.0 Ma'erkang earthquake sequence occurred in the Bayan Har block. In this paper, the temporal and spatial distribution and attenuation characteristics of earthquake sequence is analyzed based on the regional structure, the ...
Yu-ping Qi   +7 more
doaj   +1 more source

Modeling source parameters of quasi-periodic tremor

open access: yesVolcanica, 2020
Modeling harmonic tremor recorded at volcanoes is an essential practice in improving eruption forecasting methods and warning systems. We model the conduit dynamics of quasi-periodic tremor (chugging) recorded at Karymsky, Tungurahua, and Fuego volcanoes
Julian Traphagan, Jonathan Lees
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Source parameters of the M 6.5 Skyros Island (North Aegean Sea) earthquake of July 26, 2001

open access: yesAnnals of Geophysics, 2002
Teleseismic body wave modelling, time domain moment tensor inversion of regional waveforms and spectral analysis of the far-field P-wave pulses are used to derive the source parameters of the July 26, 2001 Skyros earthquake (M 6.5).
A. Kiratzi   +3 more
doaj   +1 more source

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