Results 81 to 90 of about 4,993,835 (349)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Modeling source parameters of quasi-periodic tremor

open access: yesVolcanica, 2020
Modeling harmonic tremor recorded at volcanoes is an essential practice in improving eruption forecasting methods and warning systems. We model the conduit dynamics of quasi-periodic tremor (chugging) recorded at Karymsky, Tungurahua, and Fuego volcanoes
Julian Traphagan, Jonathan Lees
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Underdetermined blind source separation based on Fuzzy C-Means and Semi-Nonnegative Matrix Factorization [PDF]

open access: yes, 2012
Conventional blind source separation is based on over-determined with more sensors than sources but the underdetermined is a challenging case and more convenient to actual situation.
Alshabrawy, Ossama S.   +3 more
core   +1 more source

Measurement-device-independent quantum key distribution with source state errors and statistical fluctuation

open access: yes, 2017
We show how to calculate the secure final key rate in the four-intensity decoy-state MDI-QKD protocol with both source errors and statistical fluctuations with a certain failure probability.
Jiang, Cong   +2 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Source parameters of the M 6.5 Skyros Island (North Aegean Sea) earthquake of July 26, 2001

open access: yesAnnals of Geophysics, 2002
Teleseismic body wave modelling, time domain moment tensor inversion of regional waveforms and spectral analysis of the far-field P-wave pulses are used to derive the source parameters of the July 26, 2001 Skyros earthquake (M 6.5).
A. Kiratzi   +3 more
doaj   +1 more source

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