Results 51 to 60 of about 14,304,572 (257)

A study of rupture characteristics of the 40 s subevent of the 1980 Irpinia earthquake

Annals of Geophysics, 1994
The Irpinia project, as carried out by ISMES under a commission from ENEL, had as objectives the developement of a general methodology to simulate broad-band seismic ground motion at near-source and regional distances, and the application of this ...
F. Pacor, A. Mendez
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Source faulting properties of the 2021 MS 6.4 Yangbi, China, earthquake sequence

Geomatics, Natural Hazards & Risk
The 2021 Yangbi earthquake sequence occurred on the southwestern margin of the Chuandian block in China, which is a typical foreshock-mainshock-aftershock sequence.
Xiangyun Guo, Xu Zhang, Lihua Fang, Dahu Li, Lei Yi   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Source parameters of the 2023 ML 6.4 Jajarkot earthquake in the western Nepal seismic gap zoneKey points

Earthquake Science
The 2023 local magnitude (ML) 6.4 Jajarkot earthquake was the most destructive event to occur in the source region of the 1505 MW8.2 Lo Mangthang Mustang earthquake in western Nepal.
Sanjev Dhakal, Ling Bai, Bowen Song, Guohui Li, Md. Moklesur Rahman, Hui Su, Zhiwen Chen, Shaojun Wang, Hongru Li, Li Li   +9 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

The Achilles tendon total rupture score : a study of responsiveness, internal consistency and convergent validity on patients with acute Achilles tendon ruptures [PDF]

, 2012
Background The Achilles tendon Total Rupture Score was developed by a research group in 2007 in response to the need for a patient reported outcome measure for this patient population.
Costa, Matthew L., Lamb, S. E. (Sallie E.), Parsons, Nicholas R., Kearney, Rebecca S., Achten, Juul, Achten, J, Lamb, Sarah, Costa, ML, Kearney Rebecca S, Achten Juul, Parsons, N, Lamb Sarah E, Parsons Nicholas, Costa Matthew L, Kearney, RS, Rebecca S Kearney, Nicholas Parsons, Matthew L Costa, Sarah E Lamb, Juul Achten   +19 more
core   +1 more source

2014年云南鲁甸MW6.1地震强地面运动模拟

Dizhen xuebao
基于震源运动学模型，采用宽频带混合模拟方法，对2014年鲁甸MW6.1地震开展了考虑复杂震源破裂过程的地震动模拟，将代表性场点的模拟结果与实际观测的强震记录进行对比，分析了不同震源模型对场点强地面运动特征影响的差异。结果表明：就震源尺度有限的中等地震而言，地震矩相近的不同震源破裂模型对震中距稍远场点的地震动影响差异相对较小，而对近震源区场点的地震动特征影响差异则较为明显。此外，不同震源模型模拟的地震动参数空间分布结果显示，不同震源模型对地震动的空间分布形态具有显著影响。
Yijun Liu, Xiaojun Li, Xiaofen Zhao, Chao Xu, Zengping Wen   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source