Results 41 to 50 of about 14,304,572 (257)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

State of the protein-synthesizing function of the placenta with premature rupture of membranes [PDF]

, 2014
Zelynskyy O O, Domakova N V. State of the protein-synthesizing function of the placenta with premature rupture of membranes. Journal of Health Sciences. 2014;4(14):57-62. ISSN 1429-9623 / 2300-665X.
Domakova, N V, Zelynskyy, O O
core   +1 more source

Verification of high rupture speed of the 1990 Luzon earthquake, Philippines from Taiwan seismic network observations

Geoscience Letters
On July 16, 1990, a Mw 7.7 earthquake struck central Luzon, Philippines. The event produced more than 100 km of surface rupture along the Philippine Fault system. Seismologists conducted detailed investigations of the overall source rupture process using
Bor-Shouh Huang, Bartolome C. Bautista, Po-Fei Chen, Chin-Shang Ku, Ishmael Narag, Emi Ulfiana, Arnaldo Melosantos, Bryan Nadimpally   +7 more
doaj   +1 more source

Source Processes of the March 2007 Singkarak Earthquakes Inferred from Teleseismic Data

Journal of Mathematical and Fundamental Sciences, 2014
The rupture processes of two sequentialearthquakes have been inverted from teleseismic data. The first event released a total seismic moment of 7.9×1018 Nm (Mw 6.5) and the slip distribution shows three asperities, 1.5 m at the shallowside, 0.7 m at the ...
Afnimar, Reiji Kobayashi, Danny Hilman Natawidjaja   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Rupture Process of the 2011 Tohoku-Oki Earthquake Based upon Joint Source Inversion of Teleseismic and GPS Data [PDF]

, 2012
This study investigated 18 broadband teleseismic records and 451 near field GPS coseismic deformation data to determine the spatial and temporal slip distribution of the 2011 Tohoku-Oki earthquake (M 9.0).
Shiann-Jong Lee
core   +2 more sources

Rupture Process of the Mw7.0 December 5, 2024 Offshore Cape Mendocino Earthquake

Geophysical Research Letters
The Mw7.0 December 5, 2024 Offshore Cape Mendocino earthquake ruptured a ∼60 km long portion of the east‐west trending Mendocino fault zone (MFZ). In order to clarify the rupture process, we assemble three‐component seismograms from regional seismic ...
F. F. Pollitz, K. A. Guns, C. E. Yoon
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Traumatic rupture of the aorta : a case report and discussion of clinical features [PDF]

, 2012
A young female patient was involved in a head-on collision and sustained a rupture of the aortic isthmus. She underwent emergency surgical repair of an aortic pseudo-aneurysm with an interposition graft.
Manche, Alexander, Tomic, Vladimir, Zerafa, Mario, Casha, Aaron R.   +3 more
core