Results 111 to 120 of about 166,223,834 (257)

Motivation and values of European Commission staff [PDF]

open access: yes, 2009
The concept of public service motivation has been central to the discussion of motivation in the field of public management but has never been studied in international organizations.
Vandenabeele, Wouter   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

What is the normativity of Meaning?

open access: yes
There has been much debate over whether to accept the claim that meaning is normative. One obstacle to making progress in that debate is that it is not always clear what the claim amounts to.
Whiting, Daniel
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The Meaning of the Old Russian Plurale Tantum PAMIATI

open access: yesSlovene, 2015
The paper deals with the meaning of the Old Russian plurale tantum pamiati, hitherto attested only in a 17th-century list of food served at banquets that is published in Ivan Zabelin’s Domashnii byt russkikh tsarei. The tentative meaning ‘brain (of crane)
Marina A. Bobrik
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Constructive use of authoritative sources in science meaning making

open access: yes, 2008
This paper was presented at the 8th International Conference of the Learning Sciences (ICLS) 2008, held in Utrecht, The Netherlands from 23 - 28 Jun 2008The role of authoritative sources of information in a constructivist learning environment has always ...
Tan, Seng Chee, Yeo, Jennifer Ai Choo
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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