Results 151 to 160 of about 223,319 (307)

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

Advanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li, Feiquan Ying, Xinkai Pang, Qiulei Wu, Guoqing Li, Lin Huang, Jiayu Xin, Xiaoli Liu, Pan Liu, Xiaohan Xu, Shuran Tan, Yumei Gao, Tong Liu, Si Sun, Xiaoman Wang, Yiping Wen, Liqiong Cai, Shi Du, Yuan Zhang, Jing Cai   +19 more
wiley   +1 more source

Genomic organization of the mouse T-cell receptor β-chain gene family [PDF]

, 1987
We have combined three different methods, deletion mapping of T-cell lines, field-inversion gel electrophoresis, and the restriction mapping of a cosmid clone, to construct a physical map of the murine T-cell receptor β-chain gene family.
Barth, Richard K., Hood, Leroy, Lai, Eric   +2 more
core  

Three Distinct Southern Blot Hybridization Patterns of HBV-DNA in the Sera of HBV Carriers.

, 1993
Miki Yamada, Motoyasu Ishii, Makoto Miura, Shuichi Sato, Atsushi Kanno, Hitoshi Ohori, Takayoshi Toyota   +6 more
openalex   +2 more sources

Transmission Dynamics of Trypanosoma cruzi Determined by Low-Stringency Single Primer Polymerase Chain Reaction and Southern Blot Analyses in Four Indigenous Communities of the Sierra Nevada de Santa Marta, Colombia [PDF]

, 2009
Ingrid Bibiana Rodríguez, Adriana Botero, Ana María Mejía‐Jaramillo, Edna J. Márquez, Sylvia Ortiz, Aldo Solari, Omar Triana‐Chávez   +6 more
openalex   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source

Challenge towards plant recombinant protein expression: instability in nuclear and chloroplast transformation

All Results Journals: Biol, 2016
It is crucial to maintain the stability of transgene and its expression level. It seems the transformation method and the target organ can influence this instability.
Mahshid Amiri, Mokhtar Jalali-Javaran, Parastoo Ehsani, Raheem Haddad   +3 more
doaj  

Analysis of Human Mitochondrial DNA Content by Southern Blotting and Nonradioactive Probe Hybridization. [PDF]

Curr Protoc Toxicol, 2019
Wheeler JH, Young CKJ, Young MJ.
europepmc   +1 more source

Several groups among human herpesvirus 6 strains can be distinguished by Southern blotting and polymerase chain reaction [PDF]

, 1991
Jean‐Thierry Aubin, H. Collandre, Daniel Candotti, Didier Ingrand, C. Rouzioux, Marianne Burgard, Sylvie Richard, J.-M. Huraux, Henri Agut   +8 more
openalex   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Bradysia hygida (Diptera, Sciaridae) presents two eukaryotic Elongation Factor 1A gene homologues: partial characterization of the eukaryotic Elongation Factor 1A-F1 gene

Brazilian Journal of Medical and Biological Research, 2010
Elongation factor 1A is a highly conserved protein that participates in translation. We report the occurrence of two genes homologous to the eukaryotic Elongation Factor 1A in Bradysia hygida and describe the partial cloning and characterization of the B.
J.A. Candido-Silva, N. Monesi
doaj