Results 151 to 160 of about 57,771 (304)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Synthetic Control Method for Dutch Policy Evaluation. [PDF]
Economist (Leiden), 2023 Verheuvel N, Witteman J, Vlaanderen M.
europepmc +1 more source
How Do Global Credit RatingAgencies Rate Firms from Developing Countries? [PDF]
, 2001 What is the relative contribution of sovereign risks and firm-level credit risks in a firm’srating assignment? Or, stated otherwise, what is the information content of these components in afirm’s rating?
Ferri, Giovanni, Liu, Li-gang
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
More analysts, better ratings: Do rating agencies invest enough in less developed countries? [PDF]
Rating agencies' track record is good in developed countries but poor in emerging economies. Why? Given the almost-monopolistic structure of the industry, we conjecture that agencies might underinvest in information gathering.
Giovanni Ferri
core
Essays in sovereign debt and sovereign credit ratings
, 2017 Defence date: 6 February 2017 Examining Board: Professor Piero Gottardi, European University Institute (Supervisor); Professor Arpad Abraham, European University Institute; Professor Luisa Lambertini , Ecole Polytechnique Federale de Lausanne; Professor Alberto Martin , Centre de Recerca en Economia Internacional This thesis consists of two chapters ...
openaire +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
THE INFLUENCE OF RATING INDICATORS IN MACROECONOMIC DECISIONS [PDF]
On the basis of major macroeconomic decisions are the internal indicators calculated by different institutions and also the rating indicators calculated by the foreign rating institutions.
Iordache Ana Maria Mihaela
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Structural Power of the State-Finance Nexus: Systemic Delinking for the Right to Development. [PDF]
Development (Rome), 2022 Muchhala B.
europepmc +1 more source