Results 101 to 110 of about 15,046 (302)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Default-risky Sovereign Debt [PDF]
Not only corporate but also sovereign debtors, in particular developing countries, may get into financial difficulties. Contrary to corporate issuers, they decide themselves if they continue to fulfill their debt obligations or convert their debt.
Andreas Wiggers
core
Systemic Risk in the European Union: A Network Approach to Banks’ Sovereign Debt Exposures
International Journal of Financial Studies, 2015 This paper draws on network theory to investigate European banks’ sovereign debt exposures. Banks’ holdings of sovereign debt build a network of financial linkages with European countries that exhibits a long-tail distribution of node degrees.
Annika Westphal
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The Janus-headed salvation: sovereign and bank credit risk premia during 2008-09 [PDF]
As the global banking crisis intensified in the fall of 2008, governments announced comprehensive rescue packages for financial institutions. In this paper, we put the joint response of euro area bank and sovereign CDS premia under the microscope.
Ejsing, Jacob, Lemke, Wolfgang
core
Sovereign Debt Exposure of European Less Significant Banks: Too Small to be Bailed
Revista Galega de Economía, 2022 This paper studies the determinants of the sovereign debt portfolios of small European banks. We cover the time frame from 2010 to 2017, including the peak of the European debt crisis. Our analysis focuses on Less Significant Institutions (LSI), a group
doaj
GREEN FINANCE INTEGRATION AND SOVEREIGN EUROBOND YIELDS IN KENYA: A CLIMATE RISK PREMIUM PERSPECTIVE
International Studies JournalKenya's exposure to climate risks and fiscal volatility has raised concerns about the pricing of its sovereign Eurobonds in global markets. This study investigates the impact of green finance announcements, ESG risk scores, and inflation on Kenya’s ...
ABDULRASAQ MUSTAPHA
doaj +1 more source
COVID-induced sovereign risk in the euro area: When did the ECB stop the spread? [PDF]
Eur Econ Rev, 2021 Ortmans A, Tripier F.
europepmc +1 more source
Non-Defaultable Debt and Sovereign Risk
IMF Working Papers, 2014 Abstract We quantify gains from introducing limited financing through non-defaultable debt into a model of equilibrium sovereign risk. For an initial sovereign spread of 4.2%, introducing the possibility of issuing non-defaultable debt for up to 10% of aggregate income reduces immediately the spread to 1.5%, and implies a welfare gain equivalent to a
Juan Carlos Hatchondo +2 more
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source