Results 31 to 40 of about 24,253 (258)

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su   +4 more
wiley   +1 more source

Changes of phytoestrogens daidzein, genistein and their glycosides daidzin and genistin and coumestrol during processing of soyabeans

open access: yesCzech Journal of Food Sciences, 2004
Phytoestrogens represent biologically active compounds showing estrogenic activity similar to that of sex hormones - estrogens. Various adverse effects such as sterility, increase of females' genitals, lost of males' copulation activity, etc.
J. Lojza, V. Schulzová, J. Hajšlová
doaj   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

open access: yesAdvanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang   +9 more
wiley   +1 more source

Producción de soya (Glycine max L.) bajo tres sistemas de labranza

open access: yesActa Agronómica, 1987
<p>The goals of this consisted in economically analyzing the conventional pattern with regard to minimum tillage and non tillage; evaluating the influence of the tillage systems on the physical properties of the soil and on the soybean's growth and
Rojas Palacio Hernán   +2 more
doaj  

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

open access: yesAdvanced Science, EarlyView.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang   +13 more
wiley   +1 more source

Efecto del riego y profundidad de compactación en la producción de soya variedad valluna-5

open access: yesActa Agronómica, 1992
<p>El experimento se realizó durante el segundo semestre de 1992 en el Centro de Investigaciones del ICA en Palmira, con el objetivo de evaluar el efecto de diferentes profundidades de compactación y niveles de  humedad sobre la producción de soya ...
Gallardo B. Carlos A.   +1 more
doaj  

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

open access: yesAdvanced Science, EarlyView.
ABSTRACT Plastic food containers used in food delivery may pose underrecognized health risks by releasing micro‐ and nanoplastics (MNPs), especially when in contact with oil‐rich foods. Here, we show that cooking oil dramatically increased MNP release from polypropylene (PP) and polyethylene (PE)‐coated containers within 3 min of microwave heating ...
Ruwen Xie   +17 more
wiley   +1 more source

Multi‐Targeting Non‐Specific Genome Engineering in Bacteria

open access: yesAdvanced Science, EarlyView.
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun   +7 more
wiley   +1 more source

Reflexiones sobre el monocultivo de soya transgénica en Argentina: Una aproximación desde la geografía del azar tecnológico

open access: yesGestión y Ambiente, 2006
Desde la geografía del azar tecnológico, el presente artículo pretende formular algunas reflexiones sobre las transformaciones territoriales generadas por la intensificación del uso de plaguicidas (herbicidas, especialmente) tras el ingreso de la soya ...
Omar Javier Ramírez H.
doaj  

Fluorinated Hypoxia‐Responsive Aza‐BODIPY for NIR‐II FL/19F MR/PA Imaging and Phototherapy of Lung Cancer

open access: yesAdvanced Science, EarlyView.
Fluorinated N‐oxide aza‐BODIPY nanoemulsions integrate fluorination‐driven molecular design with co‐assembly in fluorinated oil for multimodal imaging‐guided phototherapy. The co‐assembly redshifts fluorescence into the NIR‐II window for deep‐tissue imaging and provides a unified 19F signal for background‐free, quantitative MRI.
Anfeng Li   +5 more
wiley   +1 more source

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