Results 181 to 190 of about 233,070 (248)

Impact of Monomer Purity on the Acid‐Catalyzed ROP of Sarcosine N‐Carboxyanhydrides: A Comparative Study of Phosgene‐Free Synthetic Routes toward High‐Molecular‐Weight Polysarcosine

open access: yesMacromolecular Rapid Communications, EarlyView.
A robust, phosgene‐free oxalyl chloride/silyl‐mediated route yields high‐purity sarcosine N‐carboxyanhydride (Sar‐NCA) by eliminating residual impurities that compromise polymerization control. This strategy enables well‐defined, acid‐catalyzed ring‐opening polymerization under ambient conditions, producing polysarcosine with Mn up to 186 kDa and ...
Anna Golunova   +6 more
wiley   +1 more source

Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean   +16 more
wiley   +1 more source

Lewy Body Disease Across Aging: Clinical and Neuropathological Correlates in a Population Brain Bank

open access: yesMovement Disorders, EarlyView.
Abstract Background Lewy body disease (LBD) is defined by neuronal α‐synuclein pathology, but how Braak‐staged LBD relates to mixed neuropathology and clinical manifestations within a single population‐based cohort remains incompletely characterized. This is especially relevant in cohorts enriched for younger individuals, which may better inform real ...
Vitor Ribeiro Paes   +13 more
wiley   +1 more source

Optimized Gradient Waveforms for Tensor‐Valued Diffusion MRI Under Time‐Dependent Diffusion Using Double‐Isotropic Matched Encoding (DIME)

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Spherical and linear b‐tensor encoding (STE and LTE) enables quantification of microscopic diffusion anisotropy and diffusional variance. However, such waveforms are often variably sensitive to time‐dependent diffusion, causing rotational variance and spectral mismatch.
Felix Mortensen   +6 more
wiley   +1 more source

Real‐Time Fractional Control of an Electrohydraulic System Using Low‐Cost Technology

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT Advances in control methods for electrohydraulic systems (EHS) improve performance by addressing nonlinearities and unknown parameters, although most studies are limited to numerical simulations. Furthermore, research with experimental validation often relies on high‐performance computing equipment, specialized data acquisition cards, and ...
Edgar H. Robles‐Sauceda   +5 more
wiley   +1 more source

An Approach for Computationally Efficient Yet Accurate Modeling of Vibrating Machines With Neidhart Springs

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT Accurate modeling of vibrating machines equipped with Neidhart springs is challenging due to the strong nonlinearities introduced by the elastomer–metal torsional elements and the constraints imposed by their kinematic arrangement. Multibody modeling methodologies for such vibrating machines are often computationally demanding, thus limiting ...
Davide Galli   +3 more
wiley   +1 more source

Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis

open access: yesObesity, EarlyView.
Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi   +10 more
wiley   +1 more source

Network based approach identifies miR‐145‐3p as a central regulatory hub associated to the progression from localized to metastatic medullary thyroid carcinoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor originating from calcitonin producing C‐cells and accounts for 1–5% of thyroid cancers. Total thyroidectomy is curative in localized disease (N0), whereas lymph node metastases (N1) are associated with poorer prognosis.
Anna Citarella   +24 more
wiley   +1 more source

In‐frame variants in TP53 gene identified in adult leukemia samples are predominantly deleterious: a study of the TP53 Network of Education and Research Initiative on CLL

open access: yesThe Journal of Pathology, EarlyView.
Abstract The prognostic and predictive impact of TP53 variants in leukemia led to their inclusion in diagnostic and treatment guidelines, increasing the demand for rapid, reliable laboratory analysis, interpretation, and reporting. While most TP53 variants identified in tumor samples can be interpreted using data from large‐scale functional studies ...
Šárka Pavlová   +28 more
wiley   +1 more source

Spent Artemisia arborescens as a Biowaste Filler for Melt‐Processed PBSA Biocomposites With Enhanced Disintegration and Aerobic Biodegradation

open access: yesPolymer Composites, EarlyView.
Spent Artemisia arborescens biomass, recovered after essential‐oil steam distillation, was ground and melt‐compounded with PBSA (10 and 20 wt%), yielding biocomposites with accelerated biodegradation. ABSTRACT Artemisia arborescens is a Mediterranean shrub widely used for essential oil production, generating significant amounts of spent biomass after ...
Erika Indovino   +9 more
wiley   +1 more source

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