Results 81 to 90 of about 732,131 (275)

An Active Pattern Recognition Architecture for Mobile Robots [PDF]

open access: yes, 1993
An active, attentionally-modulated recognition architecture is proposed for object recognition and scene analysis. The proposed architecture forms part of navigation and trajectory planning modules for mobile robots.
Aguilar, J. Mario   +1 more
core   +1 more source

Estimation of Space-Time Varying Parameters Using a Diffusion LMS Algorithm

open access: yes, 2014
We study the problem of distributed adaptive estimation over networks where nodes cooperate to estimate physical parameters that can vary over both space and time domains.
Abdolee, Reza   +2 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

An Intelligent Sample Selection Method for Space-Time Adaptive Processing in Heterogeneous Environment

open access: yesIEEE Access, 2019
In the heterogeneous interference and target-rich environment, the clutter-plus-noise covariance matrix (CCM) estimate with a good match for the cell under test is significant for space–time adaptive processing.
Chongdi Duan, Yu Li, Wei Wei Wang
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Research Progress of Space-Time Adaptive Detection for Airborne Radar

open access: yesLeida xuebao, 2014
Compared with Space-Time Adaptive Processing (STAP), Space-Time Adaptive Detection (STAD) employs the data in the cell under test and those in the training to form reasonable detection statistics and consequently decides whether the target exists or not.
Wang Yong-liang   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Minimum Bit-Error Rate Design for Space-Time Equalisation-Based Multiuser Detection

open access: yes, 2006
A novel minimum bit-error rate (MBER) space–time equalization (STE)-based multiuser detector (MUD) is proposed for multiple-receive-antenna-assisted space-division multiple-access systems. It is shown that the MBER-STE-aided MUD significantly outperforms
Chen, S., Hanzo, L., Livingstone, A.
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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