Results 31 to 40 of about 13,348,458 (329)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Exploring the landscape of reflection [PDF]

, 2016
open4noopenFrison, Daniela; Fedeli, Monica; Tino, Concetta; Minnoni, ErikaFrison, Daniela; Fedeli, Monica; Tino, Concetta; Minnoni ...
Fedeli, Monica, Frison, Daniela, Minnoni, Erika, Tino, Concetta   +3 more
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Target Space $\neq$ Space

, 2015
16 pages, 1 figure; based on a presentation at the The Philosophical Foundations of Dualities in Physics conference, University of Florence, September 2014.
openaire   +3 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

n-spaces

Communications Faculty Of Science University of Ankara Series A1Mathematics and Statistics, 2020
An incidence structure with neighbour relation \(\mathbb{S}_n(R)\) over a local ring \(R\), called \(n\)-space, is defined. For \(n=2\), this is the projective Klingenberg plane over \(R\), but for \(n>2\) it is not a Klingenberg structure (with an ordinary projective space as epimorphic image).
openaire   +6 more sources

Realizing spaces as classifying spaces [PDF]

Proceedings of the American Mathematical Society, 2016
Which spaces occur as a classifying space for fibrations with a given fibre? We address this question in the context of rational homotopy theory. We construct an infinite family of finite complexes realized (up to rational homotopy) as classifying spaces. We also give several non-realization results, including the following: the rational homotopy types
Lupton, Gregory, Smith, Samuel Bruce
openaire   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source