Results 31 to 40 of about 12,256,776 (281)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
A Study of Energy and Locality Effects using Space-filling Curves [PDF]
, 2016 The cost of energy is becoming an increasingly important driver for the operating cost of HPC systems, adding yet another facet to the challenge of producing efficient code. In this paper, we investigate the energy implications of trading computation for
Jahre, Magnus +2 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Electromagnetic form factor via Bethe-Salpeter amplitude in Minkowski space
, 2008 For a relativistic system of two scalar particles, we find the Bethe-Salpeter amplitude in Minkowski space and use it to compute the electromagnetic form factor.
J. Carbonell +3 more
core +5 more sources
Non-equilibrium phenomena and molecular reaction dynamics: mode space, energy space and conformer space [PDF]
, 2013 status ...
Glowacki, David R. +2 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Momentum space properties from coordinate space electron density
, 2005 Electron density and electron momentum density, while independently tractable experimentally, bear no direct connection without going through the many-electron wave function.
Anjali Kshirsagar +4 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Phase space path integral in curved space [PDF]
, 2000 Phase space path integral is worked out in a riemannian geometry, by employing a prescription for the infinitesimal propagator that takes riemannian normal coordinates and momenta on an equal footing.
Ferraro, R., Leston, M.
core +3 more sources