Results 51 to 60 of about 6,544,337 (290)
, 2023 The Eisenhower Center for Space and Defense Studies organized the Summer Space Seminar since 2007 to advance two principal goals: (1) to foster an education and interest in the interdisciplinary areas of space with the intent to develop space ...
Space and Defense
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An Educational Introduction to ITAR and EAR Regarding Pressure Suits and Space Suits
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Space and the Vision–Language Interface: A Model-Theoretic Approach
Biolinguistics, 2011 The relation between spatial vision and spatial language has always been a source of controversy. Three problems can be identified as in need of a solution.
Francesco-Alessio Ursini
doaj +1 more source
The Role of Roadside Shrines in the Everyday Lives of Female Devotees in Mumbai
South Asia Multidisciplinary Academic Journal, 2018 This article aims to better understand the relationship between women, roadside shrines, and the urban streetscape in Mumbai. Our embodied experiences in space are gendered, and whether we are talking about real or imagined opportunities and limitations,
Anna Charlotta Osterberg
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Проект БайкалA thing, being placed in space, like in aitch-two-oh, despising the risk, longs to displace the space; but your eye does not notice the splashes of space on the floor. J. Brodsky.
Елена Григорьева
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source