Results 41 to 50 of about 6,544,337 (290)
Spatiotemporal distribution of ionospheric irregularities over India during St. Patrick’s Day Storm [PDF]
, 2022 The irregularities formed over the equatorial ionospheric region over the Indian sector have been studied for the first time for the day of the most intense geomagnetic storm of solar cycle-24, which occurred on 17.03.2015, using Rate of TEC Index (ROTI)
Acharya, Rajat ; Space Applications Centre, Ahmedabad Indian Space Research Organization
core +5 more sources
Knowledge spaces and learning spaces [PDF]
, 1920 How to design automated procedures which (i) accurately assess the knowledge of a student, and (ii) efficiently provide advices for further study? To produce well-founded answers, Knowledge Space Theory relies on a combinatorial viewpoint on the assessment of knowledge, and thus departs from common, numerical evaluation.
Doignon, Jean-Paul +1 more
openaire +5 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
“Plastic Migrants” and Deprived Livelihoods: Re-settlement and Forced Migration
Migracijske i etničke teme, 2016 “Voluntary” out-migration is anything but voluntary or driven by “free” volition. Forced migration and displacement in turn draw the gaze to the complexities and fraught realities imbricated in certain compelled contexts of “displacements” and movements ...
Maheshvari Naidu
doaj +1 more source
Realizing spaces as classifying spaces [PDF]
Proceedings of the American Mathematical Society, 2016 Which spaces occur as a classifying space for fibrations with a given fibre? We address this question in the context of rational homotopy theory. We construct an infinite family of finite complexes realized (up to rational homotopy) as classifying spaces.
Lupton, Gregory, Smith, Samuel Bruce
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Covering spaces of paracompact spaces [PDF]
Proceedings of the American Mathematical Society, 1975 This note proves that in the context of paracompact spaces, a definition used by the author implies the definition used by Saul Lubkin which does not involve the usual connectedness properties associated with covering spaces.
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source