Results 41 to 50 of about 2,434,368 (257)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

“In Space” or “As Space”?: A New Model [PDF]

open access: yesLife, 2012
In this analysis natural systems are posed to subsystemize in a manner facilitating both structured information/energy sharing and an entropy maximization process projecting a three-dimensional, spatial, outcome. Numerical simulations were first carried out to determine whether n × n input-output matrices could, once entropy-maximized, project a three ...
Smith, Charles H, Derr, Megan
openaire   +3 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Spatial displacement of numbers on a vertical number line in spatial neglect

open access: yesFrontiers in Human Neuroscience, 2015
Previous studies that investigated the association of numbers and space in humans came to contradictory conclusions about the spatial character of the mental number magnitude representation and about how it may be influenced by unilateral spatial neglect.
Urszula eMihulowicz   +7 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Processes in Space

open access: yesTheoretical Computer Science, 2010
We introduce a geometric process algebra based on affine geometry, with the aim of describing the concurrent evolution of geometric structures in 3D space. We prove a relativity theorem stating that algebraic equations are invariant under rigid body transformations.
Luca Cardelli, Philippa Gardner
openaire   +4 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

RESEARCH OF SPACE AND TIME AS A SUBJECT OF THE ART OF PAINTING (on the example of the works of the contemporary Moldovan artists Valeriu and Ion Jabinschi) [PDF]

open access: yesStudiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2018
The modern era has many characteristics that not only connect it with the previous historical stages, but also emphasize its features in the general historical and cultural process.
Iudina Ecaterina , Comendant Tatiana
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

space

open access: yesПроект Байкал
A thing, being placed in space, like in aitch-two-oh, despising the risk, longs to displace the space; but your eye does not notice the splashes of space on the floor. J. Brodsky.
Елена Григорьева
doaj   +1 more source

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