Results 31 to 40 of about 2,434,368 (257)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Expert consensus on safety and health risk assessment for suborbital space tourism (2026 edition)
Xin yixueThe rapid development of suborbital commercial spaceflight has gradually transformed space tourism from a conceptual vision into tangible reality, presenting entirely new challenges for medical screening of ordinary passengers. Suborbital flight involves
Space Medicine Collaborative Study Group
doaj +1 more source
Space and Time as A Priori Forms in the Works of Hermann Cohen and Ivan Lapshin
Кантовский сборник, 2022 In the late nineteenth and early twentieth centuries the need to rethink the status of space and time which Kant considered to be a priori forms of sensibility was prompted by the emergence of new approaches to the methodology of scientific cognition. In
V.I. Savintsev, V.S. Popova
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Analyzing physical spaces as a means of understanding rhetoric
Prompt, 2020 The following collaborative project is designed to encourage students to investigate how rhetoric functions in everyday locations. Specifically, this assignment prompts students to document, analyze, and present the physical design and makeup of ...
Roger Chao
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Test Spaces for Normal Spaces [PDF]
Proceedings of the American Mathematical Society, 1962 Let Q be a class of topological spaces. For X in Q, let dim X denote the dimension of X defined in terms of finite open coverings. If Q is the class of all normal spaces, then the dimension of spaces X in Q is characterized by the following theorem [2, p. 212]: dimX^n if, and only if, given any closed subset C of X, any continuous mapping of C into the
openaire +2 more sources