Results 31 to 40 of about 6,366,300 (284)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Conceptual Urban Quality Space-Place Framework: Linking Geo-Information and Quality of Life
Urban Science, 2018 Space and place are key concepts for understanding the functionality of social and environmental interactions. Cities are complex social-ecological systems where space–place interactions can be interpreted by means of quality of life.
Pablo F. Cabrera-Barona +1 more
doaj +1 more source
Space and Time as A Priori Forms in the Works of Hermann Cohen and Ivan Lapshin
Кантовский сборник, 2022 In the late nineteenth and early twentieth centuries the need to rethink the status of space and time which Kant considered to be a priori forms of sensibility was prompted by the emergence of new approaches to the methodology of scientific cognition. In
V.I. Savintsev, V.S. Popova
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Theoretical Computer Science, 2010 We introduce a geometric process algebra based on affine geometry, with the aim of describing the concurrent evolution of geometric structures in 3D space. We prove a relativity theorem stating that algebraic equations are invariant under rigid body transformations.
Luca Cardelli, Philippa Gardner
openaire +5 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Expert consensus on safety and health risk assessment for suborbital space tourism (2026 edition)
Xin yixueThe rapid development of suborbital commercial spaceflight has gradually transformed space tourism from a conceptual vision into tangible reality, presenting entirely new challenges for medical screening of ordinary passengers. Suborbital flight involves
Space Medicine Collaborative Study Group
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Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Analyzing physical spaces as a means of understanding rhetoric
Prompt, 2020 The following collaborative project is designed to encourage students to investigate how rhetoric functions in everyday locations. Specifically, this assignment prompts students to document, analyze, and present the physical design and makeup of ...
Roger Chao
doaj +1 more source