Results 81 to 90 of about 13,348,458 (329)

Tool-use Extends Peripersonal Space Boundaries in Schizophrenic Patients [PDF]

open access: bronze, 2022
Francesca Ferroni   +11 more
openalex   +1 more source

Space law and space resources [PDF]

open access: yes
Space industrialization is confronting space law with problems that are changing old and shaping new legal principles. The return to the Moon, the next logical step beyond the space station, will establish a permanent human presence there.
Goldman, Nathan C.
core   +1 more source

Covering spaces of paracompact spaces [PDF]

open access: yesProceedings of the American Mathematical Society, 1975
This note proves that in the context of paracompact spaces, a definition used by the author implies the definition used by Saul Lubkin which does not involve the usual connectedness properties associated with covering spaces.
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Space test program of high-voltage solar array-space plasma interactions [PDF]

open access: yes, 1985
Future spacecraft, notably the proposed Space Station, will require power systems much larger than have previously been flown. It is recognized that at higher voltages, and at the relatively high plasma density present at low Earth orbital altitudes ...
Carruth, M. R., Jr., Purvis, C. K.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Harmonized multi‐metric and multi‐centric assessment of EEG source space connectivity for dementia characterization [PDF]

open access: gold, 2023
Pavel Prado   +11 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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