Results 81 to 90 of about 6,544,337 (290)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

On Conjugate Spaces of Nakano Spaces [PDF]

open access: yesTransactions of the American Mathematical Society, 1959
The Nakano space is a normed space. The relations between the modular and its norms are the most important problem in the theory of Nakano spaces. To determine the types of modulars whose norms are proportional has been completely solved by Amemiya [1 ] and Yamamuro [1]. The purpose of this paper is to consider the relations from another point of view,
openaire   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A heterotopic perception of ‘wall’ in psychological thriller films: a place, a labyrinth and a panoptic power

open access: yesCogent Arts & Humanities
A wall is often viewed simply as a structure that divides and isolates different worlds, spaces, or places. However, an alternative perspective, known as the heterotopic point of view, suggests that a wall can be seen as a place.
Lama B. Abuhassan, Mays M. Dweiri
doaj   +1 more source

Constructions of Space: Exploring Photographic Images in Forest School

open access: yesPRISM, 2023
This research builds on the recently published paper (Garden, 2022c), which explored through interviews the use of iPads as cameras to enhance Forest School practice. Children’s perspectives of the Forest School space captured what was important to them
Ange Garden
doaj  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Jugglers Arts Space Containers [PDF]

open access: yes, 2013
The design and installation for the Jugglers Arts Space Containers was an invited commission by Jugglers Arts Space for the Containveral Festival at Northshore Hamilton (EDQ). The community festival involved a suite of custom designed and fitted shipping
Lindquist, Marissa   +4 more
core   +1 more source

Agile in Orbit: Enabling Our Mission Partners to Thrive in the Ever-Changing Space Domain

open access: yes
At SDL, agility is a quality of both our mission approach and our space ...
Space Dynamics Laboratory
core   +1 more source

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