Results 61 to 70 of about 3,436,251 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Navigating Disputes Beyond Earth: A Critical Analysis of the PCA Outer Space Rules

open access: yesAnali Pravnog Fakulteta u Beogradu
The rapid commercialization of outer space, including satellite deployment, space tourism, and asteroid mining, has created an urgent need for effective dispute settlement mechanisms.
Mohammad Owais FAROOQUI   +3 more
doaj   +1 more source

Prevention of NEO hazard: the Russian approach

open access: yesOpen Astronomy, 2021
Russian Academy of Sciences (RAS) is actively working to solve the problem of preventing Near-Earth Object (NEO) hazard. The article provides the goals and objectives of preventing NEO hazard, as well as ways to achieve them.
Pavlova Elena, Voropaev Viktor
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

THE INFLUENCE OF ‘GANG BARU’ TRADITIONAL MARKET ACTIVITIES IN THE USE OF PUBLIC SPACE IN SEMARANG CHINATOWN [PDF]

open access: yes, 2016
Chinatown is one of the commercial district in Semarang city, which continues to grow in the city center. It’s a 'generator' that drives a wide variety of economic activities, also self-actualization and disclosure of aspiration, expression of the people.
Fiton Dwi, Setiawan, Rina, Kurniati
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Taking Measure of the Universe [PDF]

open access: yes, 2000
This is a poster with classroom activities related to NASA’s Space Interferometry Mission. It introduces measurement and scale using hands-on activities.

core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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