Results 81 to 90 of about 701,390 (314)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Administrative-Legal Regulation of Ukraine’s Space Activities: Challenges in Wartime and Strategic Perspectives [PDF]
Advanced Space LawThis article examines the administrative and legal mechanisms for coordinating Ukraine’s space activities during martial law and post-war recovery. Particular attention is paid to the impact of large-scale armed aggression on the development of the space
Inesa Kostenko
doaj +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The challenges in drafting national law for space activities: A Brazilian experience
, 2014 The international space law regime mandates that individual nation states are both responsible and liable for their respective national space activities. This is one of the most important norms of space law, which face today more than never the challenge
RIBEIRO VIANA, TATIANA
core
Soft Laws relating to Space Activities
In light of the difficulties in reaching binding legal documents with increasingly diversified space interests, soft laws have been taking up more and more important roles in the regulation of space activities in recent years.
Zhao, Yun
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
, 2013 in the last decade several initiatives have been launched at the international level to face the challenge of space sustainability through soft law instruments. The first basket is composed by the technical set of rules adopted for space debris .
MARCHISIO, Sergio
core
Appreciating What's Beautiful about Space
, 2023 "Appreciating What's Beautiful about Space" uses a critical perspective to explore spaceflight culture and the appreciation of space exploration in the United States.
Schwartz, James S.J.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Regulation of space activities in Australia
, 2010 From a space perspective, as a result of the Radiocommunciations Act 1992, Australia claims jurisdiction over ‘Australian space objects’. This Act describes and defines, in detail, the process when dealing with satellite applications.
Siemon, Noel, Freeland, Steven
core