Results 101 to 110 of about 3,436,251 (315)

Overview of free-piston Stirling technology at the NASA Lewis Research Center [PDF]

, 1985
An overview of the National Aeronautics and Space Administration (NASA) Lewis Research Center (Lewis) free-piston Stirling engine activities is presented.
Slaby, J. G.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Role of States in Regulating Space Activities in International Law [PDF]

فصلنامه علوم و فناوری فضایی, 2017
International regulations consist of rights and obligations of states in relation to space. States should respect the international obligations with all of their public and private sectors.
H. Kazemi, Ali Akbar Golro
doaj  

Impact of shuttle environment on prelaunch handling of nickel-hydrogen batteries [PDF]

, 1986
Deployment of the American Satellite Company 1 spacecraft for the Space Shuttle Discovery in August 1985 set a new milestone in nickel-hydrogen battery technology.
Green, R. S.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Aeronautics and space report of the President, 1980 activities [PDF]

The year's achievements in the areas of communication, Earth resources, environment, space sciences, transportation, and space energy are summarized and current and planned activities in these areas at the various departments and agencies of the Federal ...

core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Japanese space policy: An international legal perspective

Японские исследования
Japan’s advancements in technology and its strategic focus on space policy have driven swift advancements in the field, attributed to Japan’s ability to balance scientific exploration, industrial growth, and national defense.
A. N. Vylegzhanin, M. R. Yuzbashyan, M. E. Muntian   +2 more
doaj   +1 more source

Medical operations and life sciences activities on space station [PDF]

Space station health maintenance facilities, habitability, personnel, and research in the medical sciences and in biology are discussed. It is assumed that the space station structure will consist of several modules, each being consistent with Orbiter ...
Johnson, P. C., Mason, J. A.
core   +1 more source