Results 91 to 100 of about 704,873 (314)
Maintaining Long-Term Sustainability of Outer Space Activities: Creation of regulatory framework to guide Asia-Pacific Space Cooperation Organization and selected legal issues [PDF]
, 2019 This article provides a summary on the origins of the concept of the Long-Term Sustainability of Outer Space Activities (LTSOSA) by reviewing previous discussions related to the definition of this concept with the conclusion that the LTSOSA is in fact ...
Yan, Y
core +1 more source
Administrative-Legal Regulation of Ukraine’s Space Activities: Challenges in Wartime and Strategic Perspectives [PDF]
Advanced Space LawThis article examines the administrative and legal mechanisms for coordinating Ukraine’s space activities during martial law and post-war recovery. Particular attention is paid to the impact of large-scale armed aggression on the development of the space
Inesa Kostenko
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
NASA Technical Exhibit: Space for the Benefit of Mankind, Seattle World's Fair, 1962 [PDF]
, 1962 From the introduction: The National Aeronautics and Space Administration (NASA) is a civilian agency established in 1958 by the Congress of the United States to control and manage the Nation's programs for peaceful aeronautical and space activities ...
National Aeronautics and Space Administration
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
National space law. The case of France ad new challenges for space activities [PDF]
, 2017 Space activities are risked and the increase level of commercial and private interests in outer space lead States on developing national legal frameworks for space activities, particularly with regard of their responsibilities.
Anne-Sophie Martin
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Editorial: crime patterns in time and space: the dynamics of crime opportunities in urban areas [PDF]
, 2015 The routine activity approach and associated crime pattern theory emphasise how crime emerges from spatio-temporal routines. In order to understand this crime should be studied in both space and time. However, the bulk of research into crime patterns and
Marcus Felson +6 more
core +1 more source