Results 91 to 100 of about 8,796,735 (303)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The challenges in drafting national law for space activities: A Brazilian experience
The international space law regime mandates that individual nation states are both responsible and liable for their respective national space activities. This is one of the most important norms of space law, which face today more than never the challenge
RIBEIRO VIANA, TATIANA
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
in the last decade several initiatives have been launched at the international level to face the challenge of space sustainability through soft law instruments. The first basket is composed by the technical set of rules adopted for space debris .
MARCHISIO, Sergio
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Commercial outer space activities [PDF]
The history of the Law of the space. Commercial space actions under the conditions of the corpus iuris spatialis. The Law of space, private enterprise and private property. Communications via satellite. Space transportation.
Vitale, Salvatore
core +2 more sources
Fault diagnosis for space utilisation
The space application task is to carry out various scientific experiments and applied research by using the ability of space experiment of spacecraft.
Yuanyuan Sun +4 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Purpose. This study simulates the application of the results of space activities to solve regional socio-economic development problems in the Russian Federation and develops scientific and methodological approaches to its qualitative and quantitative ...
Yuliya V. Vertakova +1 more
doaj
Space debris mitigation activities: Italian Space Agency delegation report (2019)
The space debris mitigation activities carried out in Italy between the 36th and the 37th IADC Plenary Meeting are ...
Anselmo L, Vellutini E
core

