Results 111 to 120 of about 3,436,251 (315)

Continuous space representations of human activity spaces

open access: yes, 2005
Arbeitsberichte Verkehrs- und Raumplanung ...
Vaze, Vikrant S.   +2 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Optical Activities as Computing Resources for Space-time Symmetries

open access: yes, 2009
It is known that optical activities can perform rotations. It is shown that the rotation, if modulated by attenuations, can perform symmetry operations of Wigner's little group which dictates the internal space-time symmetries of elementary particles ...
Azzam RMA   +5 more
core   +1 more source

Spaces seeking activities - activities seeking spaces: Evaluation and policy design of neighbourhood-wide urban community spaces

open access: yesCity, Culture and Society
Cities thrive on the vibrant interplay of community-driven initiatives and the adaptive reuse of public spaces that foster socio-cultural activities, enriching civic life. However, these grassroots efforts often confront challenges such as spatial inadequacies caused by bureaucratic zoning policies and the scarcity of affordable real estate.
Blečić, Ivan   +3 more
openaire   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Legal considerations and cooperative opportunities for space commercial activities [PDF]

open access: yes
It is a national policy to make the capabilities of the Space Transportation System available to a wide range of potential users. This includes its availability as a space manufacturing facility for commercial activities, which may be carried out on a ...
Hosenball, S. N.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Summary of activities of Aeronautics and Space Engineering Board [PDF]

open access: yes
Activities of the Aeronautics and Space Engineering Board (ASEB) are discussed with emphasis on space station ...

core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Compilation and development of K-6 aerospace materials for implementation in NASA spacelink electronic information system [PDF]

open access: yes
Spacelink is an electronic information service to be operated by the Marshall Space Flight Center. It will provide NASA news and educational resources including software programs that can be accessed by anyone with a computer and modem.
Blake, Jean A.
core   +1 more source

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