Results 121 to 130 of about 704,635 (314)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Activities of the Space Advanced Research Team at the University of Glasgow [PDF]
, 2008 A wide range of technologies and methodologies for space systems engineering are currently being developed at the University of Glasgow. Much of the work is centred on mission analysis and trajectory optimisation, complemented by research activities in ...
Vasile, M., Radice, G.
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, 2019 This article provides a summary on the origins of the concept of the Long-Term Sustainability of Outer Space Activities (LTSOSA) by reviewing previous discussions related to the definition of this concept with the conclusion that the LTSOSA is in fact ...
Yan, Y
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
NASA Technical Exhibit: Space for the Benefit of Mankind, Seattle World's Fair, 1962
, 1962 From the introduction: The National Aeronautics and Space Administration (NASA) is a civilian agency established in 1958 by the Congress of the United States to control and manage the Nation's programs for peaceful aeronautical and space activities ...
National Aeronautics and Space Administration
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
An Economic Assessment of Space Solar Power as a Source of Electricity for Space-Based Activities [PDF]
We develop a conceptual model of the economic value of space solar power (SSP) as a source of power to in-space activities, such as spacecraft and space stations.
Davis, James, Macauley, Molly
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
National space law. The case of France ad new challenges for space activities
, 2017 Space activities are risked and the increase level of commercial and private interests in outer space lead States on developing national legal frameworks for space activities, particularly with regard of their responsibilities.
Anne-Sophie Martin
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source