Results 51 to 60 of about 1,126,883 (314)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Space Weather and Low‐Altitude Drone Economy

open access: yesSpace Weather
Unmanned Aerial Vehicles (UAVs) are becoming integral to the emerging low‐altitude economy, operating primarily below 3,000 m for applications such as logistics, inspection, precision agriculture, and urban air mobility.
Dabin Xue   +3 more
doaj   +1 more source

A concept of space for building classification, product modelling, and design

open access: yes, 2000
Information about a building's spaces is of interest in every stage of the construction and facility management processes. An organisation1 or enterprise is located in and uses the building's spaces, and many of the building's spatial properties are ...
Ekholm, Anders   +4 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Solar Radio Wide‐Band Spectroscopy and Imaging Facilities of the Chinese Meridian Project Phase II

open access: yesSpace Weather
Solar eruptions, including flares and coronal mass ejections, are the most energetic phenomena in the solar system. These explosive events accelerate high‐energy particles and generate electromagnetic radiation from radio to gamma‐ray wavelengths ...
Yihua Yan   +19 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Validation of Neutral Wind in the Mesopause Measured by a Dual‐Channel Optical Interferometer (DCOI) Network of the Chinese Meridian Project

open access: yesSpace Weather
A Dual‐Channel Optical Interferometer (DCOI) based on Asymmetric Spatial Heterodyne Spectroscopy technique has been deployed at 11 stations by Phase II of the Chinese Meridian Project, establishing a ground‐based network for routine neutral wind ...
W. J. Liu   +10 more
doaj   +1 more source

An EOF Analysis of Water Vapor in the Middle Atmosphere and Lower Thermosphere Based on TIMED/SABER

open access: yesRemote Sensing
As a critical trace gas and a sensitive indicator of climate change, water vapor (H2O) plays a pivotal role in regulating the Earth’s radiative budget and middle-atmospheric chemical cycles.
Hongyu Liang   +5 more
doaj   +1 more source

A comparison of green space indicators for epidemiological research [PDF]

open access: yes, 2011
<p><b>Background</b> The potential for natural environments to be salutogenic has received growing interest from epidemiologists, but there has been no critical examination of the extent to which associations between green space and ...
Astell-Burt, Thomas (R16977)   +9 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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