Results 101 to 110 of about 28,333,951 (294)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Harmonic Analysis of the space BV

Revista Matemática Iberoamericana, 2003
We establish new results on the space BV of functions with bounded variation. While it is well known that this space admits no unconditional basis, we show that it is "almost" characterized by wavelet expansions in the following sense: if a function f is in BV, its coefficient sequence ...
Cohen, Albert, Dahmen, Wolfgang, Daubechies, Ingrid, DeVore, Ronald   +3 more
openaire   +3 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The economic impact of space weather: where do we stand? [PDF]

, 2016
Space weather describes the way in which the Sun, and conditions in space more generally, impact human activity and technology both in space and on the ground. It is now well understood that space weather represents a significant threat to infrastructure
Green, L, R. Wicks, Bisi, M. M., M. A. Hapgood, R. D. Bentley, Bisi, MM, Biffis, E., Bentley, R. D., McKinnell, L.-A., J. P. Eastwood, Eastwood, JP, E. Biffis, McKinnell, LA, L. Green, Burnett, C., Wicks, Robert, Wicks, R, L.-A. McKinnell, M. Gibbs, Hapgood, M. A., Burnett, C, Biffis, E, C. Burnett, Bentley, RD, Green, L., Eastwood, J, M. M. Bisi, Eastwood, J. P., Gibbs, M., Gibbs, M, Hapgood, MA   +30 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

A topological analysis of the space of recipes

International Journal of Gastronomy and Food Science
In recent years, the use of data-driven methods has provided insights into underlying patterns and principles behind culinary recipes. In this exploratory work, we introduce the use of topological data analysis, especially persistent homology, in order to study the space of culinary recipes. In particular, persistent homology analysis provides a set of
Emerson G. Escolar, Yuta Shimada, Masahiro Yuasa   +2 more
openaire   +3 more sources

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Statistically Generated Weighted Curve Fit of Residual Functions for Modal Analysis of Structures

Shock and Vibration, 1997
A statistically generated weighting function for a second-order polynomial curve fit of residual functions has been developed. The residual flexibility test method, from which a residual function is generated, is a procedure to modal test large ...
Paul Stanley Bookout
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source