Results 91 to 100 of about 28,333,951 (294)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Probability theory and causation. A branching space-times analysis [PDF]

open access: yes, 2004
We provide a formally rigorous framework for integrating singular causation, as understood by Nuel Belnap's theory of causae causantes, and objective single case probabilities.
Thomas Müller, Muller, Thomas
core   +2 more sources

High-Altitude Precision Landing by Smartphone Video Guidance Sensor and Sensor Fusion

open access: yesDrones
This paper describes the deployment, integration, and demonstration of the Smartphone Video Guidance Sensor (SVGS) as novel technology for autonomous 6-DOF proximity maneuvers and high-altitude precision landing of UAVs via sensor fusion.
Joao Leonardo Silva Cotta   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Real-time dose prediction for Artemis missions

open access: yesJournal of Space Weather and Space Climate
As large solar energetic particle (SEP) events can add significant radiation dose to astronauts in a short period of time and even induce acute clinical responses during missions, they present a concern for manned space flight operation.
Hu Shaowen   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Dayside Magnetic Depression Following Interplanetary Shock Arrivals During the February 1958 and July 1959 Superstorms

open access: yesSpace Weather
The present study investigates mid‐ and low‐latitude ground magnetic disturbances observed following the arrival of three interplanetary (IP) shocks during the super‐geomagnetic storms of February 1958 and July 1959.
Shinichi Ohtani   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A universal framework for Space Resource Utilisation (SRU) [PDF]

open access: yes, 2019
Space Resource Utilisation (SRU) or In Situ Resource Utilisation (ISRU) is the use of natural resources from the Moon, Mars and other bodies for use in situ or elsewhere in the Solar System.
Meurisse, A   +19 more
core   +1 more source

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