Results 71 to 80 of about 28,333,951 (294)

Understanding the CO2 Scrubber Used at the Space Analog for the Moon and Mars

open access: yes, 2023
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core   +1 more source

Perspectives of Global Digital Governance for Space Exploration [PDF]

open access: yesAdvanced Space Law
The article reveals the latest perspectives of global digital governance for space exploration. Approaches to the formation of a general concept of global digital governance, which is focused on ensuring security, stability and inclusiveness in the ...
Diana Levchenko
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

System Analysis of Space Missions

open access: yes, 2011
Труды сотрудников СГАУ(электрон. версия).The present laboratory practice on discipline «System Analysis of Space Missions» urged to give practical skills in carrying out of the complex analysis of almost any typical missions in a circumterraneous space ...
Belokonov V. M.   +2 more
core  

Future environmental and agricultural impacts of Brazil’s Forest Code

open access: yesEnvironmental Research Letters, 2018
The role of improving the enforcement of Brazil’s Forest Code in reducing deforestation in the Amazon has been highlighted in many studies. However, in a context of strong political pressure for loosening environmental protections, the future impacts of ...
Aline C Soterroni   +14 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Spectral Analysis in Krein Spaces

open access: yesPublications of the Research Institute for Mathematical Sciences, 1988
For a bounded #-unitary, the existence of a Tomita's triangular matrix representation is equivalent to the existence of an invariant maximal nonnegative subspace due to Pontrjagin, Krein et al. In other words, if a bounded #-unitary u has such an invariant subspace, its spectral analysis can ...
openaire   +3 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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