Results 61 to 70 of about 28,333,951 (294)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

COMPARISON OF PREDICTIVE ACCURACY OF TANAKA-JOHNSTON ANALYSIS, MELGACO FORMULA AND BHERWANI’S REGRESSION EQUATION FOR PATIENTS PRESENTING TO ARMED FORCES INSTITUTE OF DENTISTRY

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To compare Tanaka-Johnston Mixed Dentition Analyses, Melgaco’s Formula and Bherwani’s Regression Equation in predicting the widths of mandibular canine and premolars, in a population presenting to AFID.
Faheem Nake Akhtar   +5 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

OzFuel Phase A Study Report: Space-based Australian Forest Fuel Flammability Monitoring

open access: yes, 2022
• This work reports on the 14th concurrent engineering study conducted at UNSW Canberra Space Australian National Concurrent Design Facility (ANCDF) during a 5-day workshop on 21-25 February 2022.
UNSW Canberra Space
core   +1 more source

Current policies are insufficient to protect or restore Brazil’s cost-effective conservation priority zones

open access: yesEnvironmental Research Letters, 2023
In Brazil, conservation priority zones, in spite of their key role in preserving natural vegetation and its environmental resources are frequently located outside the country’s public network of protected areas (PAs).
Rafael G Ramos   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Analysis and Geometry on Configuration Spaces

open access: yesJournal of Functional Analysis, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Albeverio, Sergio   +2 more
openaire   +3 more sources

Determination of required space for canine and premolar eruption in mixed dentition using mesiodistal width of mandibular incisors

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2004
Background and Objective: Determination of the relation between periphery of dental arch and teeth size which mostly done before eruption of some permanent teeth, is of important levels of diagnosis in mixed dentition.
V Arash, A Mir Kazemi
doaj  

Retrieval ocean surface wind speed of Triton meteorological satellite mission

open access: yesTerrestrial, Atmospheric and Oceanic Sciences
Global Navigation Satellite Systems-Reflectometry (GNSS-R) technique is used to explore the Earth environment by using the Earth surface reflected GNSS signal.
Wen-Hao Yeh   +8 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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