Results 71 to 80 of about 413,850 (313)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Architecture and space for thought

open access: yes, 1988
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 21/11/1988.This thesis is concerned with the description of individual experiences of (architectural) space in a social milieu.
Glanville, Ranulph, Glanville, R
core  

An Architecture Story: Engaging Design Through Storytelling [PDF]

open access: yes, 2015
There are many historic pieces of architecture that are centuries old, but still somehow maintain the same level of magnificence and delight as they had when they were first completed.
Shek, Chuen Ho Howard
core  

A universal space-time architecture for multiple-antenna aided systems

open access: yes, 2012
In this tutorial, we first review the family of conventional multiple-antenna techniques, and then we provide a general overview of the recent concept of the powerful Multiple-Input Multiple-Output (MIMO) family based on a universal Space-Time Shift ...
Sugiura, Shinya   +2 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Architectural Support for Global Smart Spaces [PDF]

open access: yes, 2002
4th International Conference on Mobile Data Management (MDM 2003)
Alan Dearle   +8 more
openaire   +3 more sources

Abstraction/Architecture/space

open access: yes, 2007
The Abstraction/Architecture/Space’ group exhibition was concerned with the socio-spatial and intergenerational relations underpinning current contemporary practices of non-objective art in Australia.
Jenkins, Kyle
core  

Space-time shift keying: A unified MIMO architecture

open access: yes, 2010
In this paper, we propose a novel Space-Time Shift Keying (STSK) modulation scheme for Multiple-Input Multiple-Output (MIMO) communication systems, where the concept of Spatial Modulation (SM) is extended to include both the space and time dimensions, in
S. Sugiura   +5 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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