Results 151 to 160 of about 7,292 (256)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

Microcomb-enabled parallel self- calibration optical convolution streaming processor. [PDF]

open access: yesLight Sci Appl
Wang J   +15 more
europepmc   +1 more source

Recent Advances in Stimulated Brillouin Scattering in Integrated Photonics

open access: yesAdvanced Physics Research, EarlyView.
This review systematically surveys recent advances in stimulated Brillouin scattering (SBS) within integrated photonics. It begins by elucidating the fundamental mechanisms of stimulated coupling between photons and acoustic phonons in nanoscale waveguides, enhanced by the photoelastic and moving boundary effects.
Songyue Liu   +8 more
wiley   +1 more source

Guiding and Manipulating Light Fields in Microstructured Liquid Crystals

open access: yesAdvanced Physics Research, EarlyView.
This review summarizes recent advances in guided‐wave optics enabled by microstructured liquid crystal (LC) devices, covering their fundamental material properties, key degree of freedom for dynamic light field manipulations. The advances of linear guided‐wave optics, nonlinear‐optics with spatial optical solitons, and microlasers in LC‐based devices ...
Shan‐shan Chang   +2 more
wiley   +1 more source

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

open access: yesThe Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Comparative transcriptional profiling of key macrophage and fibroblast subpopulations in rheumatoid arthritis‐associated lung disease

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib   +8 more
wiley   +1 more source

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