Results 111 to 120 of about 555,969 (265)

Performance-Based Shelf Space Plan Evaluation for Enhanced Retail Efficiency

Verimlilik Dergisi
Purpose: The purpose of this paper is to introduce a performance-based planogram evaluation method to address the gap in research regarding the effectiveness of planogram implementation over time and across different retail stores.Methodology: The study ...
Şeyda Serdarasan
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Weak cementation characteristics of Jurassic sandy mudstone and its creep behavior under multi-axial loadings

International Journal of Coal Science & Technology
Jurassic sandy mudstone formations are common in the Ordos mining area, and the diagenetic period is relatively late. The lithological characteristics and creep mechanical properties of this formation form the basis for the long-term stability of ...
Qingheng Gu, Changxiang Wang, Guangming Zhao, Xuesheng Liu, Qing Ma, Weiyao Guo, Xiaosong Wen, Wenlong Lu   +7 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Space-Efficient Conversions from SLPs

We give algorithms that, given a straight-line program (SLP) with $g$ rules that generates (only) a text $T [1..n]$, builds within $O(g)$ space the Lempel-Ziv (LZ) parse of $T$ (of $z$ phrases) in time $O(n\log^2 n)$ or in time $O(gz\log^2(n/z))$. We also show how to build a locally consistent grammar (LCG) of optimal size $g_{lc} = O(δ\log\frac{n}δ ...
Travis Gagie, Adrián Goga, Artur Jez, Gonzalo Navarro 0001   +3 more
openaire   +2 more sources

Exploring the spatial-temporal differences and relational characteristics between LSE and subsystems efficiency in Chinese cities

Discover Sustainability
Effective land space utilization is crucial for the sustainable transformation of cities, and the role of land space subsystems in land space utilization is fundamental.
Qiang Li, Wei Gao
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source