Results 31 to 40 of about 7,500 (214)
The ever-growing desire to explore the cosmos compels us to seek more efficient and sustainable methods for space travel. Conventional rocket propulsion, reliant on the expulsion of propellant, presents limitations in terms of cost and environmental ...
Mostafa Essam Eissa
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Elevator noise is one of noise pollution that affect the living quality of residents. Because of the lack of accurate measurement methods and evaluation indexes for the indoor noise caused by elevator operation, the contradiction between residents ...
Junning Li +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Elevator Control Simulation Using Fuzzy Logic Management
The use of a permanent magnet synchronous motor as an actuator in a ropeless elevator presents a number of difficulties that must be overcome for the system to be secure and stable.
Mehr Ali Qasimi, Asmatullah Nashir
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The braking system is a critical safety mechanism for elevators, making precise performance prediction essential for robust design. However, high-speed elevator braking is a complex nonlinear dynamic process featuring real-time stick-slip transitions at ...
Zhongxu Tian +3 more
doaj +1 more source
The elevator pitch is part of a global tendency toward homogenization of entrepreneurial content in educational programs (Fletcher, 2018), and this article shows how the pitch is naturalized as a new language because it must be decoded in order to pass ...
Nicolai Nybye
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A new aeroservoelastic modeling and analysis methodology is presented for an aircraft with multiple control surface freeplay nonlinearities using the fictitious mass approach.
Utku Yurtsever +2 more
doaj +1 more source

