Results 41 to 50 of about 7,500 (214)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The construction of high-rise flats to minimize urban slum areas in Indonesia still create space use behavior problems for its residents due to the changes of space configuration between high-rise landed housing.
Ridwana Rifan +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Oklahoma-Auschwitz: America, Kafka's first novel [PDF]
Novel America consists of a series of fragments. It is built on the principles of expansion and compression, where the writer describes in detail what happened to Carl Rosmman, the main character of the novel (for instance, the conversation in the ...
Kostić Dragomir J.
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Novel Partial Space Elevator via an Electrodynamic Tether for Cargo Transportation
A novel partial space elevator for cargo transportation is proposed with a conceptual design of an electrodynamic tether to provide clean and propellant-free driving force for climbing motions and to control the coupled attitude motions of tethers.
Caoqun Luo +4 more
doaj +1 more source
Development of a Highly Maneuverable Walking Aid
Walking aids are vehicles that need to carry a major part of the user's weight and to run on roads. Therefore, automotive engineering was applied in this study to improve the walking aid design. The walking aid developed can turn in a small space such as
Masao Ishihama +3 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Royal Plaza Mall Surabaya experiences significant increases in visitor numbers during weekends and holiday seasons. This tendency is leading to circulation congestion and limited accessibility. This study analyzes the relationships among circulation
Rezaldy Andriansyah Miftahurahman +1 more
doaj +1 more source

