Results 51 to 60 of about 185,419 (317)
CHANGE OF RUSSIA’S COMPETITIVE POSITIONS IN THE WORLD MARKET OF SPACE PRODUCTS
Вестник университета, 2019 Subject of research – the Russian space industry against the background of the main trends of development of the world market of space products. Research objective – to give an assessment to specifics of the competition in the main segments of the world ...
A. P. Krishtofor
doaj +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Вестник университета, 2019 The present stage of development of the international scientific and technical cooperation in the space industry has been investigated. The main shifts, happening in the geographical directions of the international scientific and technical cooperation in
A. P. Krishtofor
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Research on a public-private partnership scheme for space industry creation
Nihon Kikai Gakkai ronbunshuThe purpose of this paper is to present a new open innovation type public-private partnership scheme in the space sector, which is suitable for the space industrial complex in Japan, to promote R&D and to realize national projects by public R&D ...
Shinichi TAKATA, Kazuyoshi HIDAKA
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Betatron Acceleration of Suprathermal Electrons Upstream of the Martian Bow Shock
The Astrophysical Journal, 2023 Betatron acceleration, a plasma process obtaining particle energy in the perpendicular direction but reserving energy in the field-aligned direction, is the consequence of magnetic strength enhancement when the first adiabatic invariant is conserved ...
Z. Wang +4 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source