Results 71 to 80 of about 253,613 (313)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Recent Brazilian initiatives to address legal gaps and barriers that negatively impact the development of the national space industry

open access: yes, 2017
When trying to construct a national space industry, developing nations are often hindered by limited financial resources and a lack of technical expertise.
RIBEIRO VIANA, TATIANA
core  

Innovate and prosper: ensuring Australia's future competitiveness through university-industry collaboration [PDF]

open access: yes, 2015
Executive summary The continuation of Australia’s economic growth is under threat. In order to sustain the levels of prosperity we have previously experienced, we have to build on our competitive edge in key industries to remain globally competitive ...
Australian Industry Group   +2 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Exploring the Multifaceted Landscape of Space Industry Applications: Thematic Analysis of Strategic Policy Plans of Developed and Developing Countries [PDF]

open access: yesعلوم، فناوری و کاربردهای فضایی
In recent decades, the exploration and use of space has transformed from a mere scientific curiosity to a cornerstone of technological innovation.
Arash Hashemi   +7 more
doaj   +1 more source

Telecommunications Industry Ombudsman 2016 annual report

open access: yes, 2016
The Telecommunications Industry Ombudsman (TIO) finds itself in a telecommunications landscape that is going through significant change, with new converging technologies and the roll out of major infrastructure.
Telecommunications Industry Ombudsman
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

MACROECONOMIC ASPECTS OF THE ANALYSIS OF THE WORLD MARKET OF SPACE PRODUCTS AND SERVICES

open access: yesВестник университета, 2019
The main organizational characteristics of the world space industry in the context of increased international competition have been determined. The most characteristic changes in the global market of space products have been identified.
A. Krishtofor
doaj   +1 more source

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