Results 71 to 80 of about 10,478,981 (396)

European retrospective: the European aerospace industry 1970-2000 [PDF]

, 2001
The success of Airbus Industrie in challenging Boeing’s dominant position in the highly competitive civil airliner market has been widely reported. In the light of this success this paper reviews the progress made by the European aerospace industry in ...
Smith, D
core  

Approaches to the clustering methodology in the rocket and space industry as a factor in the formation of a universal production model for the economic development in the space industry

INCAS Bulletin, 2019
Today, approaches and principles that have been retrospectively established in the rocket and space industry when forming vertically integrated structures created on the principles of corporate association or property merger need to be revised and ...
S. E. Tsybulevsky, I. M. Murakaev, P. E. Studnikov, A. Ryapukhin   +3 more
semanticscholar   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

European development experience on energy storage wheels for space [PDF]

, 1984
High speed fiber composite rotors suspended by contactless magnetic bearings were produced. European industry has acquired expertise in the study and fabrication of energy storage wheels and magnetic suspension systems for space.
Robinson, A. A.
core   +1 more source

Approaches to Active Tourism in the Urals and in Perm Krai [PDF]

, 2016
Located in the south of Ural, Perm Krai, apart from mineral resources and well-developed industry, can boast vast areas that lend themselves to active and qualified tourism, with the quality of an amateur sport.
Korolev, Andriej Y., Mishlavtceva, Swietlana E., Safarian, Azat A., Ziryanov, Aleksander I.   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

New Product Development Program Management Capability in Open Innovation Environment (Case Study: Space Industry) [PDF]

بهبود مدیریت, 2015
This article focused on recognizing the program management capabilities in open innovation environment. When organizations use open innovation and networks for their programs and projects, they need to acquire and promote new capabilities for managing ...
Mahdi Delavari, Mohammad Hossein Sobhiyah, Mohammad Reza Arasti, Seyed Kamal Tabaian, Tahmores Hasangholipor   +4 more
doaj  

An Overview and Comparison of Aviation and Space Insurance [PDF]

, 2019
Commercial aviation and commercial space operations entail significant risk. The very nature of these operations means a mishap can result in significant financial losses.
Suchodolski, Jeanne
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source