Results 71 to 80 of about 7,176,902 (304)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Space Act 2015: Towards Recognizing the Need for Space Traffic Management Regulation? [PDF]

open access: yes, 2015
Space Traffic Management can be described as technical and regulatory provisions required for guaranteeing safe and interference free operations during launch, suborbital and orbital space activities and atmospheric re-entry.
Ellis, Kim (S32724), Ellis, Kim
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Industrial Data Spaces

open access: yes, 2022
AbstractThis chapter describes the application of the IDS principles, architectural artifacts, and technologies to the application domain of industrial production and smart manufacturing, in particular as drafted by the Platform Industrie 4.0 in their Reference Architecture Model Industrie 4.0 (RAMI4.0) and follow-on specifications about the Asset ...
Thomas Usländer, Andreas Teuscher
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

EESAGAN: Edge-Enhanced and Structure-Aware GAN for Remote Sensing Image Super-Resolution

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Remote sensing (RS) images often suffer from spatial resolution degradation and edge blurring due to sensor limitations and complex degradation factors such as atmospheric turbulence and motion.
Yin Zhang   +5 more
doaj   +1 more source

Betatron Acceleration of Suprathermal Electrons Upstream of the Martian Bow Shock

open access: yesThe Astrophysical Journal, 2023
Betatron acceleration, a plasma process obtaining particle energy in the perpendicular direction but reserving energy in the field-aligned direction, is the consequence of magnetic strength enhancement when the first adiabatic invariant is conserved ...
Z. Wang   +4 more
doaj   +1 more source

The Commercial Space Industry and Launch Market [PDF]

open access: yes, 2012
The report discusses how the space industry is a subset of the U.S. aerospace industry and U.S. strength in aerospace has helped to provide U.S. strength in space. It also points out manufacturing for commercial space and employment in the U.S.
Harrison, Glennon J.
core  

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