Results 61 to 70 of about 10,478,981 (396)

Research on a public-private partnership scheme for space industry creation

open access: yesNihon Kikai Gakkai ronbunshu
The purpose of this paper is to present a new open innovation type public-private partnership scheme in the space sector, which is suitable for the space industrial complex in Japan, to promote R&D and to realize national projects by public R&D ...
Shinichi TAKATA, Kazuyoshi HIDAKA
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Exploring the Multifaceted Landscape of Space Industry Applications: Thematic Analysis of Strategic Policy Plans of Developed and Developing Countries [PDF]

open access: yesعلوم، فناوری و کاربردهای فضایی
In recent decades, the exploration and use of space has transformed from a mere scientific curiosity to a cornerstone of technological innovation.
Arash Hashemi   +7 more
doaj   +1 more source

Methods of business processes competitiveness increasing of the rocket and space industry enterprise

open access: yesIOP Conference Series: Materials Science and Engineering, 2019
This article observes problems of the branches of the Russian defense industry complex. The short comparative analysis of scientific approaches and applied methods of management of innovative business processes of the enterprise of the rocket and space ...
A. Kukartsev   +5 more
semanticscholar   +1 more source

Affordable, Rapid Bootstrapping of the Space Industry and Solar System Civilization [PDF]

open access: yes, 2016
Advances in robotics and additive manufacturing have become game-changing for the prospects of space industry. It has become feasible to bootstrap a self-sustaining, self-expanding industry at reasonably low cost.
P. Metzger   +3 more
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

MACROECONOMIC ASPECTS OF THE ANALYSIS OF THE WORLD MARKET OF SPACE PRODUCTS AND SERVICES

open access: yesВестник университета, 2019
The main organizational characteristics of the world space industry in the context of increased international competition have been determined. The most characteristic changes in the global market of space products have been identified.
A. Krishtofor
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Assessment of Socio-economic Impacts of Investments in Space Industry [PDF]

open access: yesفناوری در مهندسی هوافضا, 2020
This paper aims to assess the socio-economic impacts of space investments. It briefly propses the benefits derived from space programs. Also, it emphasizes the impact of the ever-growing trend of space technology trasfer, space commercialization, and the
Mahdi Gholami
doaj  

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