Results 51 to 60 of about 253,613 (313)

Influence of the Martian crustal magnetic fields on the Mars-solar wind interaction and plasma transport

open access: yesFrontiers in Astronomy and Space Sciences, 2023
The plasma transport process is important for the ionosphere of Mars, which controls the structure of the ionosphere above an altitude of 200 km. Plasma transport from the dayside ionosphere is crucial for producing the nightside ionosphere on Mars.
Guokan Li   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Research on a public-private partnership scheme for space industry creation

open access: yesNihon Kikai Gakkai ronbunshu
The purpose of this paper is to present a new open innovation type public-private partnership scheme in the space sector, which is suitable for the space industrial complex in Japan, to promote R&D and to realize national projects by public R&D ...
Shinichi TAKATA, Kazuyoshi HIDAKA
doaj   +1 more source

Leveraging Business Model Innovation in the International Space Industry

open access: yes, 2014
This chapter provides insights on the dynamics of the space industry, which, despite its remarkable potential, tends to remain an under-studied sector within the field of business studies.
Louis Brennan   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

DEVELOPMENT OF INNOVATIVE PROCESSES IN THE COMPANIES OF SPACE INDUSTRY

open access: yesМодернизация, инновация, развитие, 2016
In this article, the proposals to improve the theoretical and methodological base for the development of innovative technologies aerospace industry are made based on an analysis of its current state and the study of the factors influencing this process ...
Katrina B. Dobrova
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CHANGE OF RUSSIA’S COMPETITIVE POSITIONS IN THE WORLD MARKET OF SPACE PRODUCTS

open access: yesВестник университета, 2019
Subject of research – the Russian space industry against the background of the main trends of development of the world market of space products. Research objective – to give an assessment to specifics of the competition in the main segments of the world ...
A. P. Krishtofor
doaj   +1 more source

Space Situational Awareness Workshop

open access: yes, 2023
The goal of the Space Situational Awareness workshops is to bring together stakeholders interested in space situational awareness (SSA). This includes practitioners, users of data, representatives of industry and the military, the scientific community ...
Space and Defense
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy