Results 61 to 70 of about 185,419 (317)
The relevance of this study is driven by the critical importance of developing high-tech and knowledge-intensive industries for the Russian economy.
A. E. Sergeeva
doaj +1 more source
Abstract Because of its specific, industrial space, a challenge from the planning stage to the design stage is constituted. Proper zoning of this space has positive effects on the industrial function, spatial exposure and environmental impact. Proper creation of industrial areas means the impact of these processes on a macro scale. Local
openaire +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Factors and trends in the development of the space industry in the context of the digitalization of the economy of the Republic of Kazakhstan. [PDF]
Salykov A +3 more
europepmc +1 more source
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Assessment of Socio-economic Impacts of Investments in Space Industry [PDF]
This paper aims to assess the socio-economic impacts of space investments. It briefly propses the benefits derived from space programs. Also, it emphasizes the impact of the ever-growing trend of space technology trasfer, space commercialization, and the
Mahdi Gholami
doaj

