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Intraocular Pressure during Spaceflight and Risk of Glaucomatous Damage in Prolonged Microgravity

open access: yesEncyclopedia, 2023
Microgravity introduces diverse pathological and various physiological changes to the human body, including intraocular pressure. Astronauts may develop a constellation of symptoms and signs including optic disc edema, choroidal folds, and a hyperopic ...
Mouayad Masalkhi   +4 more
doaj   +1 more source

Expert consensus on safety and health risk assessment for suborbital space tourism (2026 edition)

open access: yesXin yixue
The rapid development of suborbital commercial spaceflight has gradually transformed space tourism from a conceptual vision into tangible reality, presenting entirely new challenges for medical screening of ordinary passengers. Suborbital flight involves
Space Medicine Collaborative Study Group
doaj   +1 more source

Ultrasound Biomicroscopy as a Novel, Potential Modality to Evaluate Anterior Segment Ophthalmic Structures during Spaceflight: An Analysis of Current Technology

open access: yesDiagnostics
Ocular health is currently a major concern for astronauts on current and future long-duration spaceflight missions. Spaceflight-associated neuro-ocular syndrome (SANS) is a collection of ophthalmic and neurologic findings that is one potential ...
Benjamin Soares   +9 more
doaj   +1 more source

Space Environment and Space Medicine

open access: yesHanggong uju uihakoeji, 2022
The space environment is a harsh space for humans who have evolved for a long time by adapting to the earth environment. The cosmic conditions that humans experience in outer space including the moon and Mars, such as altered gravity, exposure to cosmic ...
Kyu-Sung Kim
doaj   +1 more source

Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target

open access: yesiScience, 2023
Summary: We examined the effects of ∼30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone samples from four separate missions (BION-M1, rodent research [RR]1, RR9, and RR18 ...
Ryan W. Baranowski   +15 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

taVNS as a potential countermeasure for neurocognitive decline in microgravity

open access: yesFrontiers in Neuroscience
Exposure to microgravity induces significant physiological, cognitive, and psychomotor changes in the human body. While countermeasures such as resistance exercise and cardiovascular conditioning have been developed to address musculoskeletal and ...
L. Fricke   +5 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai   +4 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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