Results 41 to 50 of about 926,310 (249)

Utility of ultrasound in managing acute medical conditions in space: a scoping review

The Ultrasound Journal, 2023
Background In long-distance spaceflight, the challenges of communication delays and the impracticality of rapid evacuation necessitate the management of medical emergencies by onboard physicians. Consequently, these physicians must be proficient in tools,
Parsa Asachi, Ghadi Ghanem, Jason Burton, Haig Aintablian, Alan Chiem   +4 more
doaj   +1 more source

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

A systematic review of microgravity on reproductive systems: Implications for space biology and human health

iScience
Summary: Microgravity poses risks to mammalian reproductive health by altering gametogenesis, fertilization, and embryonic development. This review summarizes evidence from spaceflight and ground-based microgravity analogs, together with radiation ...
Chun-Fan Lung, Hsuan-Hsuan Lu, Chen-Yen Chung, Pao-Tai Lin, Yi-Chiung Hsu   +4 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Extraterrestrial regolith is hemostatic and potentially suitable for hemorrhage control in space

Research and Practice in Thrombosis and Haemostasis
Background: Long-duration space missions beyond low Earth orbit pose increased risks of injury to astronauts. Traumatic hemorrhage will be a cause of preventable death.
Nabil Ali-Mohamad, Ting-Hsuan Wang, Lih Jiin Juang, Nuoya Peng, Massimo F. Cau, Kevin Cannon, Christian J. Kastrup   +6 more
doaj   +1 more source

Optimization of RNA extraction for bacterial whole transcriptome studies of low-biomass samples

iScience, 2022
Summary: We developed a procedure for extracting maximal amounts of high-quality RNA from low-biomass producing (autotrophic) bacteria for experiments where sample volume is limited.
Tom Verbeelen, Rob Van Houdt, Natalie Leys, Ramon Ganigué, Felice Mastroleo   +4 more
doaj   +1 more source

Mapping Childhood Cancer Care Services in Oceania: Methodological Lessons From the SIOP Global Mapping Programme

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The International Paediatric Oncology Society Global Mapping Programme aims to collect data on global paediatric oncology services by continent, with Africa and Latin America completed. This study reports on the methodology and lessons learned for Oceania, a unique continent with resource disparity across countries, multiple small island ...
Trisha Soosay Raj, Christy Noble, Amy Gray, Daniel C. Moreira, Jennifer Lowe, Maite Gorostegui, Gwenda Anga, Andrew Soma, Milena Lay Dos Santos, Siobhan Cross, Erin Luttrell, Michael Sullivan, Julie Cayrol, Julia Challinor, Neil Ranasinghe, Jordana McLoone, Claire E. Wakefield   +16 more
wiley   +1 more source

The database of peptide medications for human deep-space missions demonstrates the potential for on-demand “Astropharmacy”

Frontiers in Space Technologies
With the advent of long-duration lunar and Martian space missions, health risks will increase significantly as astronauts will be exposed to prolonged periods of reduced gravity, elevated radiation levels, celestial dust, and isolated environments that ...
Rebecca C. Blum, Rebecca C. Blum, Dorra Omrani, Alina Kunitskaya, Alina Kunitskaya, Jessica E. Snyder, Jessica E. Snyder, Cynthia Bui, Philip M. Williams, David J. Loftus, Lynn J. Rothschild, Lynn J. Rothschild, Lynn J. Rothschild   +12 more
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin, Usanarat Anurathapan, Rawiwan Roongpraiwan, Potchanee Dandamrongrak, Siriporn Nakhonchai, Pawin Numthavaj, Vilawan Chirdkiatgumchai   +6 more
wiley   +1 more source

Challenges of Artificial Intelligence in Space Medicine

Space: Science & Technology, 2022
The human body undergoes many changes during long-duration spaceflight including musculoskeletal, visual, and behavioral changes. Several of these microgravity-induced effects serve as potential barriers to future exploration missions.
Ethan Waisberg, Joshua Ong, Phani Paladugu, Sharif Amit Kamran, Nasif Zaman, Andrew G. Lee, Alireza Tavakkoli   +6 more
doaj   +1 more source