Results 91 to 100 of about 710,122 (376)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Pentagon functions for scattering of five massless particles
We complete the analytic calculation of the full set of two-loop Feynman integrals required for computation of massless five-particle scattering amplitudes.
D. Chicherin, V. Sotnikov
doaj +1 more source
A construction of Hilbert spaces of analytic functions [PDF]
A simple technique is presented for constructing a measure ν \nu from a given measure so that R 2 ( K , ν ) {R^2}(K,\nu ) has certain properties. Here, R 2 (
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Non-archimedean Frechet spaces generalizing spaces of analytic functions
AbstractNuclearity of certain classes of non-archimedean Frechet spaces and their dual spaces is studied.
openaire +2 more sources
SPACES OF ANALYTIC FUNCTIONS OF TWO COMPLEX VARIABLES
Let \(f(z_1,z_2)= \sum^\infty_{m,n=0} a_{mn}z_1^m z_2^n\) be an analytic function in the polydisc \(|z_i|\leq ...
Behnam, Hazem Shaba, Srivastava, G. S.
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
On continuous linear functionals in some spaces of functions analytic in disk [PDF]
Evgeniya Gennad'evna Rodikova
openalex +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source

