Results 91 to 100 of about 710,122 (376)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Pentagon functions for scattering of five massless particles

open access: yesJournal of High Energy Physics, 2020
We complete the analytic calculation of the full set of two-loop Feynman integrals required for computation of massless five-particle scattering amplitudes.
D. Chicherin, V. Sotnikov
doaj   +1 more source

A construction of Hilbert spaces of analytic functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1979
A simple technique is presented for constructing a measure ν \nu from a given measure so that R 2 ( K , ν ) {R^2}(K,\nu ) has certain properties. Here, R 2 (
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Non-archimedean Frechet spaces generalizing spaces of analytic functions

open access: yesIndagationes Mathematicae (Proceedings), 1982
AbstractNuclearity of certain classes of non-archimedean Frechet spaces and their dual spaces is studied.
openaire   +2 more sources

SPACES OF ANALYTIC FUNCTIONS OF TWO COMPLEX VARIABLES

open access: yesDemonstratio Mathematica, 2000
Let \(f(z_1,z_2)= \sum^\infty_{m,n=0} a_{mn}z_1^m z_2^n\) be an analytic function in the polydisc \(|z_i|\leq ...
Behnam, Hazem Shaba, Srivastava, G. S.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy